Rowlands JC - Search Results

1

Aryl hydrocarbon receptor-mediated signal transduction.

Rowlands JC, Gustafsson JA. Rowlands JC, et al. Crit Rev Toxicol. 1997 Mar;27(2):109-34. doi: 10.3109/10408449709021615. Crit Rev Toxicol. 1997. PMID: 9099515 Review.

2

Human dioxin receptor chimera transactivation in a yeast model system and studies on receptor agonists and antagonists.

Rowlands JC, Gustafsson JA. Rowlands JC, et al. Pharmacol Toxicol. 1995 May;76(5):328-33. doi: 10.1111/j.1600-0773.1995.tb00156.x. Pharmacol Toxicol. 1995. PMID: 7567784

3

Trans-activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins: direct interactions with basal transcription factors.

Rowlands JC, McEwan IJ, Gustafsson JA. Rowlands JC, et al. Mol Pharmacol. 1996 Sep;50(3):538-48. Mol Pharmacol. 1996. PMID: 8794892

4

Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study.

Budinsky RA, Schrenk D, Simon T, Van den Berg M, Reichard JF, Silkworth JB, Aylward LL, Brix A, Gasiewicz T, Kaminski N, Perdew G, Starr TB, Walker NJ, Rowlands JC. Budinsky RA, et al. Among authors: rowlands jc. Crit Rev Toxicol. 2014 Jan;44(1):83-119. doi: 10.3109/10408444.2013.835787. Epub 2013 Nov 19. Crit Rev Toxicol. 2014. PMID: 24245878 Review.

5

Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context.

Wall RJ, He G, Denison MS, Congiu C, Onnis V, Fernandes A, Bell DR, Rose M, Rowlands JC, Balboni G, Mellor IR. Wall RJ, et al. Among authors: rowlands jc. Toxicology. 2012 Jul 16;297(1-3):26-33. doi: 10.1016/j.tox.2012.03.011. Epub 2012 Apr 7. Toxicology. 2012. PMID: 22507882 Free PMC article.

6

Fused mesoionic heterocyclic compounds are a new class of aryl hydrocarbon receptor (AhR) agonist of exceptional potency.

Wall RJ, Bell DR, Bazzi R, Fernandes A, Rose M, Rowlands JC, Mellor IR. Wall RJ, et al. Among authors: rowlands jc. Toxicology. 2012 Dec 16;302(2-3):140-5. doi: 10.1016/j.tox.2012.09.003. Epub 2012 Sep 20. Toxicology. 2012. PMID: 23000282

7

Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Phadnis-Moghe AS, Chen W, Li J, Crawford RB, Bach A, D'Ingillo S, Kovalova N, Suarez-Martinez JE, Kaplan BL, Harrill JA, Budinsky R, Rowlands JC, Thomas RS, Kaminski NE. Phadnis-Moghe AS, et al. Among authors: rowlands jc. Toxicology. 2016 Aug 10;368-369:172-182. doi: 10.1016/j.tox.2016.08.019. Epub 2016 Aug 31. Toxicology. 2016. PMID: 27590929

8

Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene.

Urban JD, Budinsky RA, Rowlands JC. Urban JD, et al. Among authors: rowlands jc. Drug Metab Pharmacokinet. 2011;26(6):637-45. doi: 10.2133/dmpk.DMPK-11-SC-031. Epub 2011 Aug 9. Drug Metab Pharmacokinet. 2011. PMID: 21828933 Free article.

9

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.

Harrill JA, Hukkanen RR, Lawson M, Martin G, Gilger B, Soldatow V, Lecluyse EL, Budinsky RA, Rowlands JC, Thomas RS. Harrill JA, et al. Among authors: rowlands jc. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. Toxicol Appl Pharmacol. 2013. PMID: 23859880

10

A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators.

Simon TW, Budinsky RA, Rowlands JC. Simon TW, et al. Among authors: rowlands jc. PLoS One. 2015 Jun 3;10(6):e0127952. doi: 10.1371/journal.pone.0127952. eCollection 2015. PLoS One. 2015. PMID: 26039703 Free PMC article.

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