Onuchic LF - Search Results

1

Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein.

Ibraghimov-Beskrovnaya O, Dackowski WR, Foggensteiner L, Coleman N, Thiru S, Petry LR, Burn TC, Connors TD, Van Raay T, Bradley J, Qian F, Onuchic LF, Watnick TJ, Piontek K, Hakim RM, Landes GM, Germino GG, Sandford R, Klinger KW. Ibraghimov-Beskrovnaya O, et al. Among authors: onuchic lf. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6397-402. doi: 10.1073/pnas.94.12.6397. Proc Natl Acad Sci U S A. 1997. PMID: 9177229 Free PMC article.

2

Macromolecular assembly of polycystin-2 intracytosolic C-terminal domain.

Ferreira FM, Oliveira LC, Germino GG, Onuchic JN, Onuchic LF. Ferreira FM, et al. Among authors: onuchic jn, onuchic lf. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9833-8. doi: 10.1073/pnas.1106766108. Epub 2011 May 27. Proc Natl Acad Sci U S A. 2011. PMID: 21622852 Free PMC article.

3

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

Qian F, Watnick TJ, Onuchic LF, Germino GG. Qian F, et al. Among authors: onuchic lf. Cell. 1996 Dec 13;87(6):979-87. doi: 10.1016/s0092-8674(00)81793-6. Cell. 1996. PMID: 8978603 Free article.

4

Somatic mutation in individual liver cysts supports a two-hit model of cystogenesis in autosomal dominant polycystic kidney disease.

Watnick TJ, Torres VE, Gandolph MA, Qian F, Onuchic LF, Klinger KW, Landes G, Germino GG. Watnick TJ, et al. Among authors: onuchic lf. Mol Cell. 1998 Aug;2(2):247-51. doi: 10.1016/s1097-2765(00)80135-5. Mol Cell. 1998. PMID: 9734362 Free article.

5

Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells.

Boletta A, Qian F, Onuchic LF, Bhunia AK, Phakdeekitcharoen B, Hanaoka K, Guggino W, Monaco L, Germino GG. Boletta A, et al. Among authors: onuchic lf. Mol Cell. 2000 Nov;6(5):1267-73. doi: 10.1016/s1097-2765(00)00123-4. Mol Cell. 2000. PMID: 11106764 Free article.

6

Biochemical characterization of bona fide polycystin-1 in vitro and in vivo.

Boletta A, Qian F, Onuchic LF, Bragonzi A, Cortese M, Deen PM, Courtoy PJ, Soria MR, Devuyst O, Monaco L, Germino GG. Boletta A, et al. Among authors: onuchic lf. Am J Kidney Dis. 2001 Dec;38(6):1421-9. doi: 10.1053/ajkd.2001.29282. Am J Kidney Dis. 2001. PMID: 11728985

7

Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.

Garcia-Gonzalez MA, Menezes LF, Piontek KB, Kaimori J, Huso DL, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG. Garcia-Gonzalez MA, et al. Among authors: onuchic lf. Hum Mol Genet. 2007 Aug 15;16(16):1940-50. doi: 10.1093/hmg/ddm141. Epub 2007 Jun 16. Hum Mol Genet. 2007. PMID: 17575307 Free PMC article.

8

Pkd1 haploinsufficiency increases renal damage and induces microcyst formation following ischemia/reperfusion.

Bastos AP, Piontek K, Silva AM, Martini D, Menezes LF, Fonseca JM, Fonseca II, Germino GG, Onuchic LF. Bastos AP, et al. Among authors: onuchic lf. J Am Soc Nephrol. 2009 Nov;20(11):2389-402. doi: 10.1681/ASN.2008040435. Epub 2009 Oct 15. J Am Soc Nephrol. 2009. PMID: 19833899 Free PMC article.

9

Renal cyst growth is the main determinant for hypertension and concentrating deficit in Pkd1-deficient mice.

Fonseca JM, Bastos AP, Amaral AG, Sousa MF, Souza LE, Malheiros DM, Piontek K, Irigoyen MC, Watnick TJ, Onuchic LF. Fonseca JM, et al. Among authors: onuchic lf. Kidney Int. 2014 May;85(5):1137-50. doi: 10.1038/ki.2013.501. Epub 2014 Jan 15. Kidney Int. 2014. PMID: 24429399 Free PMC article.

10

Genomic structure of the gene for the human P1 protein (MCM3) and its exclusion as a candidate for autosomal recessive polycystic kidney disease.

Hofmann Y, Becker J, Wright F, Avner ED, Mrug M, Guay-Woodford LM, Somlo S, Zerres K, Germino GG, Onuchic LF. Hofmann Y, et al. Among authors: onuchic lf. Eur J Hum Genet. 2000 Mar;8(3):163-6. doi: 10.1038/sj.ejhg.5200426. Eur J Hum Genet. 2000. PMID: 10780780

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