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Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.
de Haan JB, Bladier C, Griffiths P, Kelner M, O'Shea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS, Beart PM, Hertzog PJ, Kola I. de Haan JB, et al. Among authors: bronson rt. J Biol Chem. 1998 Aug 28;273(35):22528-36. doi: 10.1074/jbc.273.35.22528. J Biol Chem. 1998. PMID: 9712879 Free article.
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity.
Cao J, Schulte J, Knight A, Leslie NR, Zagozdzon A, Bronson R, Manevich Y, Beeson C, Neumann CA. Cao J, et al. EMBO J. 2009 May 20;28(10):1505-17. doi: 10.1038/emboj.2009.101. Epub 2009 Apr 16. EMBO J. 2009. PMID: 19369943 Free PMC article.
Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.
Dai C, Santagata S, Tang Z, Shi J, Cao J, Kwon H, Bronson RT, Whitesell L, Lindquist S. Dai C, et al. Among authors: bronson rt. J Clin Invest. 2012 Oct;122(10):3742-54. doi: 10.1172/JCI62727. Epub 2012 Sep 4. J Clin Invest. 2012. PMID: 22945628 Free PMC article.
The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. Wan L, et al. Among authors: bronson rt. Cancer Discov. 2017 Apr;7(4):424-441. doi: 10.1158/2159-8290.CD-16-0647. Epub 2017 Feb 7. Cancer Discov. 2017. PMID: 28174173 Free PMC article.
Kinase-independent function of E-type cyclins in liver cancer.
Geng Y, Michowski W, Chick JM, Wang YE, Jecrois ME, Sweeney KE, Liu L, Han RC, Ke N, Zagozdzon A, Sicinska E, Bronson RT, Gygi SP, Sicinski P. Geng Y, et al. Among authors: bronson rt. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1015-1020. doi: 10.1073/pnas.1711477115. Epub 2018 Jan 16. Proc Natl Acad Sci U S A. 2018. PMID: 29339491 Free PMC article.
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene.
Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA. Fazeli A, et al. Among authors: bronson rt. Nature. 1997 Apr 24;386(6627):796-804. doi: 10.1038/386796a0. Nature. 1997. PMID: 9126737
515 results