Chiba M - Search Results

1

Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans.

Chiba M, Xu X, Nishime JA, Balani SK, Lin JH. Chiba M, et al. Drug Metab Dispos. 1997 Sep;25(9):1022-31. Drug Metab Dispos. 1997. PMID: 9311616

2

Metabolite-P450 complex formation by methylenedioxyphenyl HIV protease inhibitors in rat and human liver microsomes.

Chiba M, Nishime JA, Chen IW, Vastag KJ, Sahly YS, Kim BM, Dorsey BD, Vacca JP, Lin JH. Chiba M, et al. Biochem Pharmacol. 1998 Jul 15;56(2):223-30. doi: 10.1016/s0006-2952(98)00139-7. Biochem Pharmacol. 1998. PMID: 9698076

3

Modulation of rat cytochrome P-450 by an investigational HIV protease inhibitor.

Nishime JA, Wang RW, Lin JH, Chiba M. Nishime JA, et al. Among authors: chiba m. Drug Metab Dispos. 1999 Sep;27(9):972-6. Drug Metab Dispos. 1999. PMID: 10460793

4

Effect of dexamethasone on the intestinal first-pass metabolism of indinavir in rats: evidence of cytochrome P-450 3A [correction of P-450 A] and p-glycoprotein induction.

Lin JH, Chiba M, Chen IW, Nishime JA, deLuna FA, Yamazaki M, Lin YJ. Lin JH, et al. Among authors: chiba m. Drug Metab Dispos. 1999 Oct;27(10):1187-93. Drug Metab Dispos. 1999. PMID: 10497146

5

Comparative in vitro metabolism of indinavir in primates--a unique stereoselective hydroxylation in monkey.

Chiba M, Nishime JA, Neway W, Lin Y, Lin JH. Chiba M, et al. Xenobiotica. 2000 Feb;30(2):117-29. doi: 10.1080/004982500237721. Xenobiotica. 2000. PMID: 10718120

6

Route-dependent nonlinear pharmacokinetics of a novel HIV protease inhibitor: involvement of enzyme inactivation.

Lin JH, Chen IW, Chiba M, Nishime JA, Deluna FA. Lin JH, et al. Among authors: chiba m. Drug Metab Dispos. 2000 Apr;28(4):460-6. Drug Metab Dispos. 2000. PMID: 10725315

7

Comparison of imidazole- and 2-methyl imidazole-containing farnesyl-protein transferase inhibitors: interaction with and metabolism by rat hepatic cytochrome P450s.

Tang C, Chiba M, Nishime J, Hochman JH, Chen I, Williams TM, Lin JH. Tang C, et al. Among authors: chiba m. Drug Metab Dispos. 2000 Jun;28(6):680-6. Drug Metab Dispos. 2000. PMID: 10820141

8

P450 interaction with HIV protease inhibitors: relationship between metabolic stability, inhibitory potency, and P450 binding spectra.

Chiba M, Jin L, Neway W, Vacca JP, Tata JR, Chapman K, Lin JH. Chiba M, et al. Drug Metab Dispos. 2001 Jan;29(1):1-3. Drug Metab Dispos. 2001. PMID: 11124221

9

Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor.

Chiba M, Nishime JA, Lin JH. Chiba M, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1527-34. J Pharmacol Exp Ther. 1995. PMID: 8531125

10

Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.

Chiba M, Hensleigh M, Nishime JA, Balani SK, Lin JH. Chiba M, et al. Drug Metab Dispos. 1996 Mar;24(3):307-14. Drug Metab Dispos. 1996. PMID: 8820421

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