Schellens JH - Search Results

1

Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development.

Gerrits CJ, de Jonge MJ, Schellens JH, Stoter G, Verweij J. Gerrits CJ, et al. Among authors: schellens jh. Br J Cancer. 1997;76(7):952-62. doi: 10.1038/bjc.1997.491. Br J Cancer. 1997. PMID: 9328159 Free PMC article. Review.

2

Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration.

Gerrits CJ, Creemers GJ, Schellens JH, Wissel P, Planting AS, Kunka R, Selinger K, de Boer-Dennert M, Marijnen Y, Harteveld M, Verweij J. Gerrits CJ, et al. Among authors: schellens jh. Br J Cancer. 1996 Mar;73(6):744-50. doi: 10.1038/bjc.1996.130. Br J Cancer. 1996. PMID: 8611374 Free PMC article. Clinical Trial.

3

Bioavailability and pharmacokinetics of oral topotecan: a new topoisomerase I inhibitor.

Schellens JH, Creemers GJ, Beijnen JH, Rosing H, de Boer-Dennert M, McDonald M, Davies B, Verweij J. Schellens JH, et al. Br J Cancer. 1996 May;73(10):1268-71. doi: 10.1038/bjc.1996.243. Br J Cancer. 1996. PMID: 8630291 Free PMC article. Clinical Trial.

4

Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours.

Schellens JH, Ma J, Planting AS, van der Burg ME, van Meerten E, de Boer-Dennert M, Schmitz PI, Stoter G, Verweij J. Schellens JH, et al. Br J Cancer. 1996 Jun;73(12):1569-75. doi: 10.1038/bjc.1996.296. Br J Cancer. 1996. PMID: 8664132 Free PMC article.

5

Phase II and pharmacologic study of topotecan administered as a 21-day continuous infusion to patients with colorectal cancer.

Creemers GJ, Gerrits CJ, Schellens JH, Planting AS, van der Burg ME, van Beurden VM, de Boer-Dennert M, Harteveld M, Loos W, Hudson I, Stoter G, Verweij J. Creemers GJ, et al. Among authors: schellens jh. J Clin Oncol. 1996 Sep;14(9):2540-5. doi: 10.1200/JCO.1996.14.9.2540. J Clin Oncol. 1996. PMID: 8823333 Clinical Trial.

6

Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors.

Creemers GJ, Gerrits CJ, Eckardt JR, Schellens JH, Burris HA, Planting AS, Rodriguez GI, Loos WJ, Hudson I, Broom C, Verweij J, Von Hoff DD. Creemers GJ, et al. Among authors: schellens jh. J Clin Oncol. 1997 Mar;15(3):1087-93. doi: 10.1200/JCO.1997.15.3.1087. J Clin Oncol. 1997. PMID: 9060549 Clinical Trial.

7

The bioavailability of oral GI147211 (GG211), a new topoisomerase I inhibitor.

Gerrits CJ, Schellens JH, Creemers GJ, Wissel P, Planting AS, Pritchard JF, DePee S, de Boer-Dennert M, Harteveld M, Verweij J. Gerrits CJ, et al. Among authors: schellens jh. Br J Cancer. 1997;76(7):946-51. doi: 10.1038/bjc.1997.490. Br J Cancer. 1997. PMID: 9328158 Free PMC article. Clinical Trial.

8

Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro.

Ma J, Maliepaard M, Nooter K, Boersma AW, Verweij J, Stoter G, Schellens JH. Ma J, et al. Among authors: schellens jh. Cancer Chemother Pharmacol. 1998;41(4):307-16. doi: 10.1007/s002800050744. Cancer Chemother Pharmacol. 1998. PMID: 9488600

9

Oral topotecan given once or twice daily for ten days: a phase I pharmacology study in adult patients with solid tumors.

Gerrits CJ, Burris H, Schellens JH, Eckardt JR, Planting AS, van der Burg ME, Rodriguez GI, Loos WJ, van Beurden V, Hudson I, Fields S, Von Hoff DD, Verweij J. Gerrits CJ, et al. Among authors: schellens jh. Clin Cancer Res. 1998 May;4(5):1153-8. Clin Cancer Res. 1998. PMID: 9607572 Clinical Trial.

10

Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line.

Ma J, Maliepaard M, Nooter K, Loos WJ, Kolker HJ, Verweij J, Stoter G, Schellens JH. Ma J, et al. Among authors: schellens jh. Br J Cancer. 1998 May;77(10):1645-52. doi: 10.1038/bjc.1998.270. Br J Cancer. 1998. PMID: 9635842 Free PMC article.

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