Kewn S - Search Results

1

Lamivudine (3TC) phosphorylation and drug interactions in vitro.

Kewn S, Veal GJ, Hoggard PG, Barry MG, Back DJ. Kewn S, et al. Biochem Pharmacol. 1997 Sep 1;54(5):589-95. doi: 10.1016/s0006-2952(97)00189-5. Biochem Pharmacol. 1997. PMID: 9337075

2

Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea.

Hoggard PG, Kewn S, Maherbe A, Wood R, Almond LM, Sales SD, Gould J, Lou Y, De Vries C, Back DJ, Khoo SH; CHARM Study Group. Hoggard PG, et al. Among authors: kewn s. AIDS. 2002 Dec 6;16(18):2439-46. doi: 10.1097/00002030-200212060-00009. AIDS. 2002. PMID: 12461418 Clinical Trial.

3

Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro.

Hoggard PG, Kewn S, Barry MG, Khoo SH, Back DJ. Hoggard PG, et al. Among authors: kewn s. Antimicrob Agents Chemother. 1997 Jun;41(6):1231-6. doi: 10.1128/AAC.41.6.1231. Antimicrob Agents Chemother. 1997. PMID: 9174176 Free PMC article.

4

Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.

Kewn S, Hoggard PG, Henry-Mowatt JS, Veal GJ, Sales SD, Barry MG, Back DJ. Kewn S, et al. AIDS Res Hum Retroviruses. 1999 Jun 10;15(9):793-802. doi: 10.1089/088922299310692. AIDS Res Hum Retroviruses. 1999. PMID: 10381167

5

The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.

Kewn S, Hoggard PG, Sales SD, Johnson MA, Back DJ. Kewn S, et al. Br J Clin Pharmacol. 2000 Dec;50(6):597-604. doi: 10.1046/j.1365-2125.2000.00302.x. Br J Clin Pharmacol. 2000. PMID: 11136299 Free PMC article.

6

Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression in vitro.

Hoggard PG, Sales SD, Kewn S, Sunderland D, Khoo SH, Hart CA, Back DJ. Hoggard PG, et al. Among authors: kewn s. Antivir Chem Chemother. 2000 Nov;11(6):353-8. doi: 10.1177/095632020001100601. Antivir Chem Chemother. 2000. PMID: 11227992 Free article.

7

Development of enzymatic assays for quantification of intracellular lamivudine and carbovir triphosphate levels in peripheral blood mononuclear cells from human immunodeficiency virus-infected patients.

Kewn S, Hoggard PG, Sales SD, Jones K, Maher B, Khoo SH, Back DJ. Kewn S, et al. Antimicrob Agents Chemother. 2002 Jan;46(1):135-43. doi: 10.1128/AAC.46.1.135-143.2002. Antimicrob Agents Chemother. 2002. PMID: 11751124 Free PMC article.

8

Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients.

Kewn S, Wang LH, Hoggard PG, Rousseau F, Hart R, MacNeela JP, Khoo SH, Back DJ. Kewn S, et al. Antimicrob Agents Chemother. 2003 Jan;47(1):255-61. doi: 10.1128/AAC.47.1.255-261.2003. Antimicrob Agents Chemother. 2003. PMID: 12499199 Free PMC article.

9

Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools.

Sankatsing SU, Hoggard PG, Huitema AD, Sparidans RW, Kewn S, Crommentuyn KM, Lange JM, Beijnen JH, Back DJ, Prins JM. Sankatsing SU, et al. Among authors: kewn s. Clin Pharmacokinet. 2004;43(12):823-32. doi: 10.2165/00003088-200443120-00004. Clin Pharmacokinet. 2004. PMID: 15355127 Clinical Trial.

10

Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP.

Sankatsing SU, Prins JM, Yong SL, Roelofsen J, van Kuilenburg AB, Kewn S, Back DJ, Bemelman FJ, ten Berge IJ. Sankatsing SU, et al. Among authors: kewn s. Transpl Int. 2008 Nov;21(11):1066-71. doi: 10.1111/j.1432-2277.2008.00739.x. Transpl Int. 2008. PMID: 18699845 Free article.

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