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Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, Melton DW, Tremblay P, Hood LE, Westaway D. Moore RC, et al. Among authors: chishti ma. J Mol Biol. 1999 Oct 1;292(4):797-817. doi: 10.1006/jmbi.1999.3108. J Mol Biol. 1999. PMID: 10525406
Transgenic mouse models of Alzheimer's disease.
Janus C, Chishti MA, Westaway D. Janus C, et al. Among authors: chishti ma. Biochim Biophys Acta. 2000 Jul 26;1502(1):63-75. doi: 10.1016/s0925-4439(00)00033-8. Biochim Biophys Acta. 2000. PMID: 10899432 Free article. Review. No abstract available.
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.
Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J, Strome R, Zuker N, Loukides J, French J, Turner S, Lozza G, Grilli M, Kunicki S, Morissette C, Paquette J, Gervais F, Bergeron C, Fraser PE, Carlson GA, George-Hyslop PS, Westaway D. Chishti MA, et al. J Biol Chem. 2001 Jun 15;276(24):21562-70. doi: 10.1074/jbc.M100710200. Epub 2001 Mar 15. J Biol Chem. 2001. PMID: 11279122 Free article.
New developments in animal models of Alzheimer's disease.
Janus C, Phinney AL, Chishti MA, Westaway D. Janus C, et al. Among authors: chishti ma. Curr Neurol Neurosci Rep. 2001 Sep;1(5):451-7. doi: 10.1007/s11910-001-0105-8. Curr Neurol Neurosci Rep. 2001. PMID: 11898556 Review.
In vivo reduction of amyloid-beta by a mutant copper transporter.
Phinney AL, Drisaldi B, Schmidt SD, Lugowski S, Coronado V, Liang Y, Horne P, Yang J, Sekoulidis J, Coomaraswamy J, Chishti MA, Cox DW, Mathews PM, Nixon RA, Carlson GA, St George-Hyslop P, Westaway D. Phinney AL, et al. Among authors: chishti ma. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14193-8. doi: 10.1073/pnas.2332851100. Epub 2003 Nov 14. Proc Natl Acad Sci U S A. 2003. PMID: 14617772 Free PMC article.
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.
Drisaldi B, Coomaraswamy J, Mastrangelo P, Strome B, Yang J, Watts JC, Chishti MA, Marvi M, Windl O, Ahrens R, Major F, Sy MS, Kretzschmar H, Fraser PE, Mount HT, Westaway D. Drisaldi B, et al. Among authors: chishti ma. J Biol Chem. 2004 Dec 31;279(53):55443-54. doi: 10.1074/jbc.M404794200. Epub 2004 Sep 29. J Biol Chem. 2004. PMID: 15459186 Free article.
Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.
Mastrangelo P, Mathews PM, Chishti MA, Schmidt SD, Gu Y, Yang J, Mazzella MJ, Coomaraswamy J, Horne P, Strome B, Pelly H, Levesque G, Ebeling C, Jiang Y, Nixon RA, Rozmahel R, Fraser PE, St George-Hyslop P, Carlson GA, Westaway D. Mastrangelo P, et al. Among authors: chishti ma. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8972-7. doi: 10.1073/pnas.0500940102. Epub 2005 Jun 10. Proc Natl Acad Sci U S A. 2005. PMID: 15951428 Free PMC article.
43 results