Eigenbrot C - Search Results

1

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor.

Wiesmann C, Fuh G, Christinger HW, Eigenbrot C, Wells JA, de Vos AM. Wiesmann C, et al. Among authors: eigenbrot c. Cell. 1997 Nov 28;91(5):695-704. doi: 10.1016/s0092-8674(00)80456-0. Cell. 1997. PMID: 9393862 Free article.

2

Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50AIL-8 at 2 A resolution.

Eigenbrot C, Lowman HB, Chee L, Artis DR. Eigenbrot C, et al. Proteins. 1997 Apr;27(4):556-66. Proteins. 1997. PMID: 9141135

3

Receptor-binding conformation of the "ELR" motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 A resolution.

Gerber N, Lowman H, Artis DR, Eigenbrot C. Gerber N, et al. Among authors: eigenbrot c. Proteins. 2000 Mar 1;38(4):361-7. Proteins. 2000. PMID: 10707023

4

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor.

Stamos J, Sliwkowski MX, Eigenbrot C. Stamos J, et al. Among authors: eigenbrot c. J Biol Chem. 2002 Nov 29;277(48):46265-72. doi: 10.1074/jbc.M207135200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196540 Free article.

5

Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions.

Sidhu SS, Li B, Chen Y, Fellouse FA, Eigenbrot C, Fuh G. Sidhu SS, et al. Among authors: eigenbrot c. J Mol Biol. 2004 Apr 23;338(2):299-310. doi: 10.1016/j.jmb.2004.02.050. J Mol Biol. 2004. PMID: 15066433

6

Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling.

Kirchhofer D, Yao X, Peek M, Eigenbrot C, Lipari MT, Billeci KL, Maun HR, Moran P, Santell L, Wiesmann C, Lazarus RA. Kirchhofer D, et al. Among authors: eigenbrot c. J Biol Chem. 2004 Sep 17;279(38):39915-24. doi: 10.1074/jbc.M404795200. Epub 2004 Jun 24. J Biol Chem. 2004. PMID: 15218027 Free article.

7

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.

Lee CV, Liang WC, Dennis MS, Eigenbrot C, Sidhu SS, Fuh G. Lee CV, et al. Among authors: eigenbrot c. J Mol Biol. 2004 Jul 23;340(5):1073-93. doi: 10.1016/j.jmb.2004.05.051. J Mol Biol. 2004. PMID: 15236968

8

Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist.

Kirchhofer D, Lipari MT, Santell L, Billeci KL, Maun HR, Sandoval WN, Moran P, Ridgway J, Eigenbrot C, Lazarus RA. Kirchhofer D, et al. Among authors: eigenbrot c. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5306-11. doi: 10.1073/pnas.0700184104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372204 Free PMC article.

9

A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.

Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C. Schaefer G, et al. Among authors: eigenbrot c. Cancer Cell. 2011 Oct 18;20(4):472-86. doi: 10.1016/j.ccr.2011.09.003. Cancer Cell. 2011. PMID: 22014573 Free article.

10

Oncogenic ERBB3 mutations in human cancers.

Jaiswal BS, Kljavin NM, Stawiski EW, Chan E, Parikh C, Durinck S, Chaudhuri S, Pujara K, Guillory J, Edgar KA, Janakiraman V, Scholz RP, Bowman KK, Lorenzo M, Li H, Wu J, Yuan W, Peters BA, Kan Z, Stinson J, Mak M, Modrusan Z, Eigenbrot C, Firestein R, Stern HM, Rajalingam K, Schaefer G, Merchant MA, Sliwkowski MX, de Sauvage FJ, Seshagiri S. Jaiswal BS, et al. Among authors: eigenbrot c. Cancer Cell. 2013 May 13;23(5):603-17. doi: 10.1016/j.ccr.2013.04.012. Cancer Cell. 2013. PMID: 23680147 Free article.

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