Naisbitt DJ - Search Results

1

Neutrophil cytotoxicity of the chemically reactive metabolite(s) of clozapine: possible role in agranulocytosis.

Williams DP, Pirmohamed M, Naisbitt DJ, Maggs JL, Park BK. Williams DP, et al. Among authors: naisbitt dj. J Pharmacol Exp Ther. 1997 Dec;283(3):1375-82. J Pharmacol Exp Ther. 1997. PMID: 9400013

2

Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component.

Hawley SR, Bray PG, O'Neill PM, Naisbitt DJ, Park BK, Ward SA. Hawley SR, et al. Among authors: naisbitt dj. Antimicrob Agents Chemother. 1996 Oct;40(10):2345-9. doi: 10.1128/AAC.40.10.2345. Antimicrob Agents Chemother. 1996. PMID: 8891142 Free PMC article.

3

Disposition of amodiaquine and related antimalarial agents in human neutrophils: implications for drug design.

Naisbitt DJ, Ruscoe JE, Williams D, O'Neill PM, Pirmohamed M, Park BK. Naisbitt DJ, et al. J Pharmacol Exp Ther. 1997 Feb;280(2):884-93. J Pharmacol Exp Ther. 1997. PMID: 9023303

4

The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat.

Gill HJ, Hough SJ, Naisbitt DJ, Maggs JL, Kitteringham NR, Pirmohamed M, Park BK. Gill HJ, et al. Among authors: naisbitt dj. J Pharmacol Exp Ther. 1997 Aug;282(2):795-801. J Pharmacol Exp Ther. 1997. PMID: 9262343

5

Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs.

Naisbitt DJ, Williams DP, O'Neill PM, Maggs JL, Willock DJ, Pirmohamed M, Park BK. Naisbitt DJ, et al. Chem Res Toxicol. 1998 Dec;11(12):1586-95. doi: 10.1021/tx980148k. Chem Res Toxicol. 1998. PMID: 9860505

6

Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity.

Naisbitt DJ, Hough SJ, Gill HJ, Pirmohamed M, Kitteringham NR, Park BK. Naisbitt DJ, et al. Br J Pharmacol. 1999 Mar;126(6):1393-407. doi: 10.1038/sj.bjp.0702453. Br J Pharmacol. 1999. PMID: 10217534 Free PMC article.

7

Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals.

Schnyder B, Burkhart C, Schnyder-Frutig K, von Greyerz S, Naisbitt DJ, Pirmohamed M, Park BK, Pichler WJ. Schnyder B, et al. Among authors: naisbitt dj. J Immunol. 2000 Jun 15;164(12):6647-54. doi: 10.4049/jimmunol.164.12.6647. J Immunol. 2000. PMID: 10843725

8

Induction of metabolism-dependent and -independent neutrophil apoptosis by clozapine.

Williams DP, Pirmohamed M, Naisbitt DJ, Uetrecht JP, Park BK. Williams DP, et al. Among authors: naisbitt dj. Mol Pharmacol. 2000 Jul;58(1):207-16. doi: 10.1124/mol.58.1.207. Mol Pharmacol. 2000. PMID: 10860943

9

Metabolism of lamotrigine to a reactive arene oxide intermediate.

Maggs JL, Naisbitt DJ, Tettey JN, Pirmohamed M, Park BK. Maggs JL, et al. Among authors: naisbitt dj. Chem Res Toxicol. 2000 Nov;13(11):1075-81. doi: 10.1021/tx0000825. Chem Res Toxicol. 2000. PMID: 11087428

10

Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment.

Naisbitt DJ, Gordon SF, Pirmohamed M, Park BK. Naisbitt DJ, et al. Drug Saf. 2000 Dec;23(6):483-507. doi: 10.2165/00002018-200023060-00002. Drug Saf. 2000. PMID: 11144658 Review.

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