Breakefield XO - Search Results

1

Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.

Kramm CM, Chase M, Herrlinger U, Jacobs A, Pechan PA, Rainov NG, Sena-Esteves M, Aghi M, Barnett FH, Chiocca EA, Breakefield XO. Kramm CM, et al. Among authors: breakefield xo. Hum Gene Ther. 1997 Nov 20;8(17):2057-68. doi: 10.1089/hum.1997.8.17-2057. Hum Gene Ther. 1997. PMID: 9414254

2

Gene transfer into mammalian central nervous system using herpes virus vectors: extended expression of bacterial lacZ in neurons using the neuron-specific enolase promoter.

Andersen JK, Garber DA, Meaney CA, Breakefield XO. Andersen JK, et al. Among authors: breakefield xo. Hum Gene Ther. 1992 Oct;3(5):487-99. doi: 10.1089/hum.1992.3.5-487. Hum Gene Ther. 1992. PMID: 1329993

3

Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells.

Takamiya Y, Short MP, Ezzeddine ZD, Moolten FL, Breakefield XO, Martuza RL. Takamiya Y, et al. Among authors: breakefield xo. J Neurosci Res. 1992 Nov;33(3):493-503. doi: 10.1002/jnr.490330316. J Neurosci Res. 1992. PMID: 1335091

4

Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.

Chiocca EA, Choi BB, Cai WZ, DeLuca NA, Schaffer PA, DiFiglia M, Breakefield XO, Martuza RL. Chiocca EA, et al. Among authors: breakefield xo. New Biol. 1990 Aug;2(8):739-46. New Biol. 1990. PMID: 2178004

5

Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.

Muldoon LL, Nilaver G, Kroll RA, Pagel MA, Breakefield XO, Chiocca EA, Davidson BL, Weissleder R, Neuwelt EA. Muldoon LL, et al. Among authors: breakefield xo. Am J Pathol. 1995 Dec;147(6):1840-51. Am J Pathol. 1995. PMID: 7495307 Free PMC article.

6

Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase.

Boviatsis EJ, Scharf JM, Chase M, Harrington K, Kowall NW, Breakefield XO, Chiocca EA. Boviatsis EJ, et al. Among authors: breakefield xo. Gene Ther. 1994 Sep;1(5):323-31. Gene Ther. 1994. PMID: 7584098

7

Genetically modified fibroblasts producing NGF protect hippocampal neurons after ischemia in the rat.

Pechan PA, Yoshida T, Panahian N, Moskowitz MA, Breakefield XO. Pechan PA, et al. Among authors: breakefield xo. Neuroreport. 1995 Mar 7;6(4):669-72. doi: 10.1097/00001756-199503000-00021. Neuroreport. 1995. PMID: 7605924

8

Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene.

Wei MX, Tamiya T, Chase M, Boviatsis EJ, Chang TK, Kowall NW, Hochberg FH, Waxman DJ, Breakefield XO, Chiocca EA. Wei MX, et al. Among authors: breakefield xo. Hum Gene Ther. 1994 Aug;5(8):969-78. doi: 10.1089/hum.1994.5.8-969. Hum Gene Ther. 1994. PMID: 7948146

9

Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.

Boviatsis EJ, Park JS, Sena-Esteves M, Kramm CM, Chase M, Efird JT, Wei MX, Breakefield XO, Chiocca EA. Boviatsis EJ, et al. Among authors: breakefield xo. Cancer Res. 1994 Nov 15;54(22):5745-51. Cancer Res. 1994. PMID: 7954393

10

Herpesvirus-mediated gene delivery into the rat brain: specificity and efficiency of the neuron-specific enolase promoter.

Andersen JK, Frim DM, Isacson O, Breakefield XO. Andersen JK, et al. Among authors: breakefield xo. Cell Mol Neurobiol. 1993 Oct;13(5):503-15. doi: 10.1007/BF00711459. Cell Mol Neurobiol. 1993. PMID: 8111822

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