Spaulding C - Search Results

1

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence.

Effros RB, Boucher N, Porter V, Zhu X, Spaulding C, Walford RL, Kronenberg M, Cohen D, Schächter F. Effros RB, et al. Among authors: spaulding c. Exp Gerontol. 1994 Nov-Dec;29(6):601-9. doi: 10.1016/0531-5565(94)90073-6. Exp Gerontol. 1994. PMID: 9435913

2

Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation.

Spaulding C, Guo W, Effros RB. Spaulding C, et al. Exp Gerontol. 1999 Aug;34(5):633-44. doi: 10.1016/s0531-5565(99)00033-9. Exp Gerontol. 1999. PMID: 10530789

3

The accumulation of non-replicative, non-functional, senescent T cells with age is avoided in calorically restricted mice by an enhancement of T cell apoptosis.

Spaulding CC, Walford RL, Effros RB. Spaulding CC, et al. Mech Ageing Dev. 1997 Feb;93(1-3):25-33. doi: 10.1016/s0047-6374(96)01808-8. Mech Ageing Dev. 1997. PMID: 9089568

4

The role of CD8+ T-cell replicative senescence in human aging.

Effros RB, Dagarag M, Spaulding C, Man J. Effros RB, et al. Among authors: spaulding c. Immunol Rev. 2005 Jun;205:147-57. doi: 10.1111/j.0105-2896.2005.00259.x. Immunol Rev. 2005. PMID: 15882351 Review.

5

Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-alpha and IL-6 in C3B10RF1 mice.

Spaulding CC, Walford RL, Effros RB. Spaulding CC, et al. Mech Ageing Dev. 1997 Feb;93(1-3):87-94. doi: 10.1016/s0047-6374(96)01824-6. Mech Ageing Dev. 1997. PMID: 9089573

6

Regorafenib induces DNA damage and enhances PARP inhibitor efficacy in pancreatic ductal carcinoma.

Pham TD, Becker JH, Metropulos AE, Mubin N, Spaulding C, Bentrem DJ, Munshi HG. Pham TD, et al. Among authors: spaulding c. BMC Cancer. 2024 Dec 20;24(1):1562. doi: 10.1186/s12885-024-13334-y. BMC Cancer. 2024. PMID: 39707244 Free PMC article.

7

Abbreviated or Standard Antiplatelet Therapy After PCI in Diabetic Patients at High Bleeding Risk.

Roffi M, Landi A, Heg D, Frigoli E, Chalkou K, Chevalier B, Ijsselmuiden AJJ, Kastberg R, Komiyama N, Morice MC, Onuma Y, Ozaki Y, Peace A, Pyxaras S, Sganzerla P, Williams R, Xaplanteris P, Vranckx P, Windecker S, Smits PC, Valgimigli M; MASTER DAPT Investigators. Roffi M, et al. JACC Cardiovasc Interv. 2024 Nov 25;17(22):2664-2677. doi: 10.1016/j.jcin.2024.08.030. JACC Cardiovasc Interv. 2024. PMID: 39603779 Clinical Trial.

8

Trametinib Potentiates Anti-PD-1 Efficacy in Tumors Established from Chemotherapy-Primed Pancreatic Cancer Cells.

Pham TD, Metropulos AE, Mubin N, Becker JH, Shah D, Spaulding C, Shields MA, Bentrem DJ, Munshi HG. Pham TD, et al. Among authors: spaulding c. Mol Cancer Ther. 2024 Dec 3;23(12):1854-1865. doi: 10.1158/1535-7163.MCT-23-0833. Mol Cancer Ther. 2024. PMID: 39162011

9

Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer.

Becker JH, Metropulos AE, Spaulding C, Marinelarena AM, Shields MA, Principe DR, Pham TD, Munshi HG. Becker JH, et al. Among authors: spaulding c. Cancer Res. 2024 Nov 4;84(21):3629-3639. doi: 10.1158/0008-5472.CAN-23-3574. Cancer Res. 2024. PMID: 39137400 Free PMC article.

10

BET Inhibition Rescues Acinar-Ductal-Metaplasia and Ciliogenesis and Ameliorates Chronic Pancreatitis-Driven Changes in Mice With Loss of the Polarity Protein Par3.

Shields MA, Metropulos AE, Spaulding C, Alzahrani KA, Hirose T, Ohno S, Pham TND, Munshi HG. Shields MA, et al. Among authors: spaulding c. Cell Mol Gastroenterol Hepatol. 2024;18(5):101389. doi: 10.1016/j.jcmgh.2024.101389. Epub 2024 Aug 10. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39128653 Free PMC article.

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