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Reduced insulin receptor expression and function in human colonic Caco-2 cells by ras and polyoma middle T oncogenes.
Baron-Delage S, Capeau J, Barbu V, Chastre E, Levy P, Gespach C, Cherqui G. Baron-Delage S, et al. Among authors: cherqui g. J Biol Chem. 1994 Jul 15;269(28):18686-93. J Biol Chem. 1994. PMID: 8034618 Free article.
As compared to vector control Caco-2 cells, both oncogene-transfected cells exhibited: 1) a loss of response to insulin's stimulatory effect on mitogen-activated protein (MAP) kinase activity and cell proliferation, both of which were constitutively increased; 2) a decrease in in …
As compared to vector control Caco-2 cells, both oncogene-transfected cells exhibited: 1) a loss of response to insulin's stimulatory effect …
Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase.
Bertrand F, Desbois-Mouthon C, Cadoret A, Prunier C, Robin H, Capeau J, Atfi A, Cherqui G. Bertrand F, et al. Among authors: cherqui g. J Biol Chem. 1999 Oct 22;274(43):30596-602. doi: 10.1074/jbc.274.43.30596. J Biol Chem. 1999. PMID: 10521443 Free article.
Insulin-mediated cell proliferation and survival involve inhibition of c-Jun N-terminal kinases through a phosphatidylinositol 3-kinase- and mitogen-activated protein kinase phosphatase-1-dependent pathway.
Desbois-Mouthon C, Cadoret A, Blivet-Van Eggelpoël MJ, Bertrand F, Caron M, Atfi A, Cherqui G, Capeau J. Desbois-Mouthon C, et al. Among authors: cherqui g. Endocrinology. 2000 Mar;141(3):922-31. doi: 10.1210/endo.141.3.7390. Endocrinology. 2000. PMID: 10698166
Evidence for a role of the JNK cascade in Smad7-mediated apoptosis.
Mazars A, Lallemand F, Prunier C, Marais J, Ferrand N, Pessah M, Cherqui G, Atfi A. Mazars A, et al. Among authors: cherqui g. J Biol Chem. 2001 Sep 28;276(39):36797-803. doi: 10.1074/jbc.M101672200. Epub 2001 Jul 26. J Biol Chem. 2001. PMID: 11477069 Free article.
69 results