Lukacs GL - Search Results

1

Limited proteolysis as a probe for arrested conformational maturation of delta F508 CFTR.

Zhang F, Kartner N, Lukacs GL. Zhang F, et al. Among authors: lukacs gl. Nat Struct Biol. 1998 Mar;5(3):180-3. doi: 10.1038/nsb0398-180. Nat Struct Biol. 1998. PMID: 9501909

2

The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH.

Lukacs GL, Chang XB, Kartner N, Rotstein OD, Riordan JR, Grinstein S. Lukacs GL, et al. J Biol Chem. 1992 Jul 25;267(21):14568-72. J Biol Chem. 1992. PMID: 1378835 Free article.

3

Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.

Lukacs GL, Mohamed A, Kartner N, Chang XB, Riordan JR, Grinstein S. Lukacs GL, et al. EMBO J. 1994 Dec 15;13(24):6076-86. doi: 10.1002/j.1460-2075.1994.tb06954.x. EMBO J. 1994. PMID: 7529176 Free PMC article.

4

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

Lukacs GL, Chang XB, Bear C, Kartner N, Mohamed A, Riordan JR, Grinstein S. Lukacs GL, et al. J Biol Chem. 1993 Oct 15;268(29):21592-8. J Biol Chem. 1993. PMID: 7691813 Free article.

5

Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells.

Mohamed A, Ferguson D, Seibert FS, Cai HM, Kartner N, Grinstein S, Riordan JR, Lukacs GL. Mohamed A, et al. Among authors: lukacs gl. Biochem J. 1997 Feb 15;322 ( Pt 1)(Pt 1):259-65. doi: 10.1042/bj3220259. Biochem J. 1997. PMID: 9078271 Free PMC article.

6

Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation.

Lukacs GL, Segal G, Kartner N, Grinstein S, Zhang F. Lukacs GL, et al. Biochem J. 1997 Dec 1;328 ( Pt 2)(Pt 2):353-61. doi: 10.1042/bj3280353. Biochem J. 1997. PMID: 9371688 Free PMC article.

7

Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways.

Chow YH, O'Brodovich H, Plumb J, Wen Y, Sohn KJ, Lu Z, Zhang F, Lukacs GL, Tanswell AK, Hui CC, Buchwald M, Hu J. Chow YH, et al. Among authors: lukacs gl. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14695-700. doi: 10.1073/pnas.94.26.14695. Proc Natl Acad Sci U S A. 1997. PMID: 9405675 Free PMC article.

8

C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation.

Haardt M, Benharouga M, Lechardeur D, Kartner N, Lukacs GL. Haardt M, et al. Among authors: lukacs gl. J Biol Chem. 1999 Jul 30;274(31):21873-7. doi: 10.1074/jbc.274.31.21873. J Biol Chem. 1999. PMID: 10419506 Free article.

9

Cystic fibrosis mutations lead to carboxyl-terminal fragments that highlight an early biogenesis step of the cystic fibrosis transmembrane conductance regulator.

Van Oene M, Lukacs GL, Rommens JM. Van Oene M, et al. Among authors: lukacs gl. J Biol Chem. 2000 Jun 30;275(26):19577-84. doi: 10.1074/jbc.M002186200. J Biol Chem. 2000. PMID: 10764788 Free article.

10

Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments.

Sharma M, Benharouga M, Hu W, Lukacs GL. Sharma M, et al. Among authors: lukacs gl. J Biol Chem. 2001 Mar 23;276(12):8942-50. doi: 10.1074/jbc.M009172200. Epub 2000 Dec 21. J Biol Chem. 2001. PMID: 11124952 Free article.

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