Bray PG - Search Results

1

Relationship between antimalarial drug activity, accumulation, and inhibition of heme polymerization in Plasmodium falciparum in vitro.

Hawley SR, Bray PG, Mungthin M, Atkinson JD, O'Neill PM, Ward SA. Hawley SR, et al. Among authors: bray pg. Antimicrob Agents Chemother. 1998 Mar;42(3):682-6. doi: 10.1128/AAC.42.3.682. Antimicrob Agents Chemother. 1998. PMID: 9517951 Free PMC article.

2

Novel short chain chloroquine analogues retain activity against chloroquine resistant K1 Plasmodium falciparum.

Stocks PA, Raynes KJ, Bray PG, Park BK, O'Neill PM, Ward SA. Stocks PA, et al. Among authors: bray pg. J Med Chem. 2002 Nov 7;45(23):4975-83. doi: 10.1021/jm0108707. J Med Chem. 2002. PMID: 12408708

3

Heme binding contributes to antimalarial activity of bis-quaternary ammoniums.

Biagini GA, Richier E, Bray PG, Calas M, Vial H, Ward SA. Biagini GA, et al. Among authors: bray pg. Antimicrob Agents Chemother. 2003 Aug;47(8):2584-9. doi: 10.1128/AAC.47.8.2584-2589.2003. Antimicrob Agents Chemother. 2003. PMID: 12878523 Free PMC article.

4

Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

Johnson DJ, Fidock DA, Mungthin M, Lakshmanan V, Sidhu AB, Bray PG, Ward SA. Johnson DJ, et al. Among authors: bray pg. Mol Cell. 2004 Sep 24;15(6):867-77. doi: 10.1016/j.molcel.2004.09.012. Mol Cell. 2004. PMID: 15383277 Free PMC article.

5

Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria.

Biagini GA, Viriyavejakul P, O'neill PM, Bray PG, Ward SA. Biagini GA, et al. Among authors: bray pg. Antimicrob Agents Chemother. 2006 May;50(5):1841-51. doi: 10.1128/AAC.50.5.1841-1851.2006. Antimicrob Agents Chemother. 2006. PMID: 16641458 Free PMC article.

6

Drug-regulated expression of Plasmodium falciparum P-glycoprotein homologue 1: a putative role for nuclear receptors.

Johnson DJ, Owen A, Plant N, Bray PG, Ward SA. Johnson DJ, et al. Among authors: bray pg. Antimicrob Agents Chemother. 2008 Apr;52(4):1438-45. doi: 10.1128/AAC.01392-07. Epub 2008 Jan 14. Antimicrob Agents Chemother. 2008. PMID: 18195056 Free PMC article.

7

Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure.

Ochong E, Bell DJ, Johnson DJ, D'Alessandro U, Mulenga M, Muangnoicharoen S, Van Geertruyden JP, Winstanley PA, Bray PG, Ward SA, Owen A. Ochong E, et al. Among authors: bray pg. Antimicrob Agents Chemother. 2008 Nov;52(11):3883-8. doi: 10.1128/AAC.00431-08. Epub 2008 Aug 25. Antimicrob Agents Chemother. 2008. PMID: 18725445 Free PMC article.

8

Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation.

Bray PG, Howells RE, Ritchie GY, Ward SA. Bray PG, et al. Biochem Pharmacol. 1992 Oct 6;44(7):1317-24. doi: 10.1016/0006-2952(92)90532-n. Biochem Pharmacol. 1992. PMID: 1417955

9

Vacuolar acidification and chloroquine sensitivity in Plasmodium falciparum.

Bray PG, Howells RE, Ward SA. Bray PG, et al. Biochem Pharmacol. 1992 Mar 17;43(6):1219-27. doi: 10.1016/0006-2952(92)90495-5. Biochem Pharmacol. 1992. PMID: 1562274

10

Current views on the mechanisms of resistance to quinoline-containing drugs in Plasmodium falciparum.

Ward SA, Bray PG, Mungthin M, Hawley SR. Ward SA, et al. Among authors: bray pg. Ann Trop Med Parasitol. 1995 Apr;89(2):121-4. doi: 10.1080/00034983.1995.11812942. Ann Trop Med Parasitol. 1995. PMID: 7605121

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