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The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo.
Brook B, Checkervarty AK, Barman S, Sweitzer C, Bosco AN, Sherman AC, Baden LR, Morrocchi E, Sanchez-Schmitz G, Palma P, Nanishi E, O'Meara TR, McGrath ME, Frieman MB, Soni D, van Haren SD, Ozonoff A, Diray-Arce J, Steen H, Dowling DJ, Levy O. Brook B, et al. Among authors: mcgrath me. iScience. 2024 Sep 26;27(11):111055. doi: 10.1016/j.isci.2024.111055. eCollection 2024 Nov 15. iScience. 2024. PMID: 39569372 Free PMC article.
SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression.
McGrath ME, Xue Y, Taylor L, Dillen C, Ardanuy J, Gonzalez-Juarbe N, Baracco L, Kim R, Hart R, Assad-Garcia N, Vashee S, Frieman MB. McGrath ME, et al. PLoS Pathog. 2024 May 23;20(5):e1011669. doi: 10.1371/journal.ppat.1011669. eCollection 2024 May. PLoS Pathog. 2024. PMID: 38781259 Free PMC article.
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.
O'Meara TR, Nanishi E, McGrath ME, Barman S, Dong D, Dillen C, Menon M, Seo HS, Dhe-Paganon S, Ernst RK, Levy O, Frieman MB, Dowling DJ. O'Meara TR, et al. Among authors: mcgrath me. J Allergy Clin Immunol. 2023 Nov;152(5):1107-1120.e6. doi: 10.1016/j.jaci.2023.06.031. Epub 2023 Aug 16. J Allergy Clin Immunol. 2023. PMID: 37595760 Free PMC article.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
Rodriguez-Rodriguez BA, Ciabattoni GO, Duerr R, Valero-Jimenez AM, Yeung ST, Crosse KM, Schinlever AR, Bernard-Raichon L, Rodriguez Galvan J, McGrath ME, Vashee S, Xue Y, Loomis CA, Khanna KM, Cadwell K, Desvignes L, Frieman MB, Ortigoza MB, Dittmann M. Rodriguez-Rodriguez BA, et al. Among authors: mcgrath me. Nat Commun. 2023 May 25;14(1):3026. doi: 10.1038/s41467-023-38783-0. Nat Commun. 2023. PMID: 37230979 Free PMC article.
108 results