Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin.
Huhtala P, Humphries MJ, McCarthy JB, Tremble PM, Werb Z, Damsky CH.
Huhtala P, et al. Among authors: werb z.
J Cell Biol. 1995 May;129(3):867-79. doi: 10.1083/jcb.129.3.867.
J Cell Biol. 1995.
PMID: 7537277
Free PMC article.
Rabbit synovial fibroblasts (RSF) express basal levels of the metalloproteinases (MMP) collagenase, stromelysin-1 and 92-kD gelatinase when plated on intact fibronectin (FN), but elevated levels when plated on either the central RGD-containing cell-binding region of FN (120FN) or …
Rabbit synovial fibroblasts (RSF) express basal levels of the metalloproteinases (MMP) collagenase, stromelysin-1 and 92-kD gelatinase when …