Evans WE - Search Results

1

Structural and functional analysis of the human TPMT gene promoter.

Fessing MY, Krynetski EY, Schuetz JD, Evans WE. Fessing MY, et al. Among authors: evans we. Adv Exp Med Biol. 1998;431:315-8. doi: 10.1007/978-1-4615-5381-6_62. Adv Exp Med Biol. 1998. PMID: 9598082 No abstract available.

2

Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity.

Tai HL, Krynetski EY, Schuetz EG, Yanishevski Y, Evans WE. Tai HL, et al. Among authors: evans we. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6444-9. doi: 10.1073/pnas.94.12.6444. Proc Natl Acad Sci U S A. 1997. PMID: 9177237 Free PMC article.

3

Promoter and intronic sequences of the human thiopurine S-methyltransferase (TPMT) gene isolated from a human PAC1 genomic library.

Krynetski EY, Fessing MY, Yates CR, Sun D, Schuetz JD, Evans WE. Krynetski EY, et al. Among authors: evans we. Pharm Res. 1997 Dec;14(12):1672-8. doi: 10.1023/a:1012111325397. Pharm Res. 1997. PMID: 9453052

4

Molecular cloning and functional characterization of the cDNA encoding the murine thiopurine S-methyltransferase (TPMT).

Fessing MY, Belkov VM, Krynetski EY, Evans WE. Fessing MY, et al. Among authors: evans we. FEBS Lett. 1998 Mar 13;424(3):143-5. doi: 10.1016/s0014-5793(98)00159-8. FEBS Lett. 1998. PMID: 9539138 Free article.

5

Functional characterization of the human thiopurine S-methyltransferase (TPMT) gene promoter.

Fessing MY, Krynetski EY, Zambetti GP, Evans WE. Fessing MY, et al. Among authors: evans we. Eur J Biochem. 1998 Sep 15;256(3):510-7. doi: 10.1046/j.1432-1327.1998.2560510.x. Eur J Biochem. 1998. PMID: 9780226 Free article.

6

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase.

Krynetski EY, Schuetz JD, Galpin AJ, Pui CH, Relling MV, Evans WE. Krynetski EY, et al. Among authors: evans we. Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):949-53. doi: 10.1073/pnas.92.4.949. Proc Natl Acad Sci U S A. 1995. PMID: 7862671 Free PMC article.

7

Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults.

McLeod HL, Krynetski EY, Wilimas JA, Evans WE. McLeod HL, et al. Among authors: evans we. Pharmacogenetics. 1995 Oct;5(5):281-6. doi: 10.1097/00008571-199510000-00003. Pharmacogenetics. 1995. PMID: 8563768

8

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.

Tai HL, Krynetski EY, Yates CR, Loennechen T, Fessing MY, Krynetskaia NF, Evans WE. Tai HL, et al. Among authors: evans we. Am J Hum Genet. 1996 Apr;58(4):694-702. Am J Hum Genet. 1996. PMID: 8644731 Free PMC article.

9

Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms.

Krynetski EY, Tai HL, Yates CR, Fessing MY, Loennechen T, Schuetz JD, Relling MV, Evans WE. Krynetski EY, et al. Among authors: evans we. Pharmacogenetics. 1996 Aug;6(4):279-90. doi: 10.1097/00008571-199608000-00001. Pharmacogenetics. 1996. PMID: 8873214 Review.

10

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance.

Yates CR, Krynetski EY, Loennechen T, Fessing MY, Tai HL, Pui CH, Relling MV, Evans WE. Yates CR, et al. Among authors: evans we. Ann Intern Med. 1997 Apr 15;126(8):608-14. doi: 10.7326/0003-4819-126-8-199704150-00003. Ann Intern Med. 1997. PMID: 9103127

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