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Human beta 2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-beta 2-glycoprotein I antibodies.
Del Papa N, Sheng YH, Raschi E, Kandiah DA, Tincani A, Khamashta MA, Atsumi T, Hughes GR, Ichikawa K, Koike T, Balestrieri G, Krilis SA, Meroni PL. Del Papa N, et al. Among authors: hughes gr. J Immunol. 1998 Jun 1;160(11):5572-8. J Immunol. 1998. PMID: 9605162 Free article.
Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation.
Del Papa N, Guidali L, Sala A, Buccellati C, Khamashta MA, Ichikawa K, Koike T, Balestrieri G, Tincani A, Hughes GR, Meroni PL. Del Papa N, et al. Among authors: hughes gr. Arthritis Rheum. 1997 Mar;40(3):551-61. doi: 10.1002/art.1780400322. Arthritis Rheum. 1997. PMID: 9082944
The pathophysiology of anti-phospholipid antibodies.
Meroni PL, Tincani A, Harris EN, Valesini G, Hughes GR, Balestrieri G. Meroni PL, et al. Among authors: hughes gr. Clin Exp Rheumatol. 1989 Sep-Oct;7 Suppl 3:S81-4. Clin Exp Rheumatol. 1989. PMID: 2514060 Review.
723 results