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3-and 4-substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium channel openers: synthesis, pharmacological evaluation, and structure-activity relationships.
de Tullio P, Pirotte B, Lebrun P, Fontaine J, Dupont L, Antoine MH, Ouedraogo R, Khelili S, Maggetto C, Masereel B, Diouf O, Podona T, Delarge J. de Tullio P, et al. Among authors: diouf o. J Med Chem. 1996 Feb 16;39(4):937-48. doi: 10.1021/jm9500582. J Med Chem. 1996. PMID: 8632417
4H-1,2,4-Pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2, 4-pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors: design, synthesis, pharmacology, and structure-activity relationships.
Pirotte B, Podona T, Diouf O, de Tullio P, Lebrun P, Dupont L, Somers F, Delarge J, Morain P, Lestage P, Lepagnol J, Spedding M. Pirotte B, et al. Among authors: diouf o. J Med Chem. 1998 Jul 30;41(16):2946-59. doi: 10.1021/jm970694v. J Med Chem. 1998. PMID: 9685234
30 results