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Page 1
Leukocystatin, a new Class II cystatin expressed selectively by hematopoietic cells.
Halfon S, Ford J, Foster J, Dowling L, Lucian L, Sterling M, Xu Y, Weiss M, Ikeda M, Liggett D, Helms A, Caux C, Lebecque S, Hannum C, Menon S, McClanahan T, Gorman D, Zurawski G. Halfon S, et al. Among authors: gorman d. J Biol Chem. 1998 Jun 26;273(26):16400-8. doi: 10.1074/jbc.273.26.16400. J Biol Chem. 1998. PMID: 9632704 Free article.
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo.
Fort MM, Cheung J, Yen D, Li J, Zurawski SM, Lo S, Menon S, Clifford T, Hunte B, Lesley R, Muchamuel T, Hurst SD, Zurawski G, Leach MW, Gorman DM, Rennick DM. Fort MM, et al. Among authors: gorman dm. Immunity. 2001 Dec;15(6):985-95. doi: 10.1016/s1074-7613(01)00243-6. Immunity. 2001. PMID: 11754819 Free article.
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis.
Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S, Lucian L, Geissler R, Brodie S, Kimball AB, Gorman DM, Smith K, de Waal Malefyt R, Kastelein RA, McClanahan TK, Bowman EP. Chan JR, et al. J Exp Med. 2006 Nov 27;203(12):2577-87. doi: 10.1084/jem.20060244. Epub 2006 Oct 30. J Exp Med. 2006. PMID: 17074928 Free PMC article.
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW. Parham C, et al. Among authors: gorman d. J Immunol. 2002 Jun 1;168(11):5699-708. doi: 10.4049/jimmunol.168.11.5699. J Immunol. 2002. PMID: 12023369
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.
Soumelis V, Reche PA, Kanzler H, Yuan W, Edward G, Homey B, Gilliet M, Ho S, Antonenko S, Lauerma A, Smith K, Gorman D, Zurawski S, Abrams J, Menon S, McClanahan T, de Waal-Malefyt Rd R, Bazan F, Kastelein RA, Liu YJ. Soumelis V, et al. Among authors: gorman d. Nat Immunol. 2002 Jul;3(7):673-80. doi: 10.1038/ni805. Epub 2002 Jun 10. Nat Immunol. 2002. PMID: 12055625
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA. Oppmann B, et al. Among authors: gorman d. Immunity. 2000 Nov;13(5):715-25. doi: 10.1016/s1074-7613(00)00070-4. Immunity. 2000. PMID: 11114383 Free article.
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