Robert J - Search Results

1

Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38.

Dodds HM, Haaz MC, Riou JF, Robert J, Rivory LP. Dodds HM, et al. Among authors: robert j. J Pharmacol Exp Ther. 1998 Jul;286(1):578-83. J Pharmacol Exp Ther. 1998. PMID: 9655905

2

Determination of drug interactions occurring with the metabolic pathways of irinotecan.

Charasson V, Haaz MC, Robert J. Charasson V, et al. Among authors: robert j. Drug Metab Dispos. 2002 Jun;30(6):731-3. doi: 10.1124/dmd.30.6.731. Drug Metab Dispos. 2002. PMID: 12019202

3

Molecular, cellular, and clinical aspects of the pharmacology of 20(S)camptothecin and its derivatives.

Rivory LP, Robert J. Rivory LP, et al. Among authors: robert j. Pharmacol Ther. 1995;68(2):269-96. doi: 10.1016/0163-7258(95)02009-8. Pharmacol Ther. 1995. PMID: 8719971 Review.

4

Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase.

Rivory LP, Bowles MR, Robert J, Pond SM. Rivory LP, et al. Among authors: robert j. Biochem Pharmacol. 1996 Oct 11;52(7):1103-11. doi: 10.1016/0006-2952(96)00457-1. Biochem Pharmacol. 1996. PMID: 8831730

5

Glucuronidation of SN-38, the active metabolite of irinotecan, by human hepatic microsomes.

Haaz MC, Rivory L, Jantet S, Ratanasavanh D, Robert J. Haaz MC, et al. Among authors: robert j. Pharmacol Toxicol. 1997 Feb;80(2):91-6. doi: 10.1111/j.1600-0773.1997.tb00289.x. Pharmacol Toxicol. 1997. PMID: 9060040

6

The transformation of irinotecan (CPT-11) to its active metabolite SN-38 by human liver microsomes. Differential hydrolysis for the lactone and carboxylate forms.

Haaz MC, Rivory LP, Riché C, Robert J. Haaz MC, et al. Among authors: robert j. Naunyn Schmiedebergs Arch Pharmacol. 1997 Aug;356(2):257-62. doi: 10.1007/pl00005049. Naunyn Schmiedebergs Arch Pharmacol. 1997. PMID: 9272733

7

Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions.

Haaz MC, Rivory L, Riché C, Vernillet L, Robert J. Haaz MC, et al. Among authors: robert j. Cancer Res. 1998 Feb 1;58(3):468-72. Cancer Res. 1998. PMID: 9458091

8

Biosynthesis of an aminopiperidino metabolite of irinotecan [7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecine] by human hepatic microsomes.

Haaz MC, Riché C, Rivory LP, Robert J. Haaz MC, et al. Among authors: robert j. Drug Metab Dispos. 1998 Aug;26(8):769-74. Drug Metab Dispos. 1998. PMID: 9698291

9

[Pharmacology of camptothecin and its derivatives].

Rivory LP, Robert J. Rivory LP, et al. Among authors: robert j. Bull Cancer. 1995 Apr;82(4):265-85. Bull Cancer. 1995. PMID: 10846537 Review. French.

10

Hepatic extraction, metabolism, and biliary excretion of irinotecan in the isolated perfused rat liver.

Farabos C, Haaz MC, Gires P, Robert J. Farabos C, et al. Among authors: robert j. J Pharm Sci. 2001 Jun;90(6):722-31. doi: 10.1002/jps.1028. J Pharm Sci. 2001. PMID: 11357175

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