Christinger HW - Search Results

1

VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.

Muller YA, Chen Y, Christinger HW, Li B, Cunningham BC, Lowman HB, de Vos AM. Muller YA, et al. Among authors: christinger hw. Structure. 1998 Sep 15;6(9):1153-67. doi: 10.1016/s0969-2126(98)00116-6. Structure. 1998. PMID: 9753694 Free article.

2

The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1.

Christinger HW, Fuh G, de Vos AM, Wiesmann C. Christinger HW, et al. J Biol Chem. 2004 Mar 12;279(11):10382-8. doi: 10.1074/jbc.M313237200. Epub 2003 Dec 18. J Biol Chem. 2004. PMID: 14684734 Free article.

3

Crystallization of the receptor binding domain of vascular endothelial growth factor.

Christinger HW, Muller YA, Berleau LT, Keyt BA, Cunningham BC, Ferrara N, de Vos AM. Christinger HW, et al. Proteins. 1996 Nov;26(3):353-7. doi: 10.1002/(SICI)1097-0134(199611)26:3<353::AID-PROT9>3.0.CO;2-E. Proteins. 1996. PMID: 8953654

4

Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site.

Muller YA, Li B, Christinger HW, Wells JA, Cunningham BC, de Vos AM. Muller YA, et al. Among authors: christinger hw. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7192-7. doi: 10.1073/pnas.94.14.7192. Proc Natl Acad Sci U S A. 1997. PMID: 9207067 Free PMC article.

5

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding.

Muller YA, Christinger HW, Keyt BA, de Vos AM. Muller YA, et al. Among authors: christinger hw. Structure. 1997 Oct 15;5(10):1325-38. doi: 10.1016/s0969-2126(97)00284-0. Structure. 1997. PMID: 9351807 Free article.

6

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor.

Wiesmann C, Fuh G, Christinger HW, Eigenbrot C, Wells JA, de Vos AM. Wiesmann C, et al. Among authors: christinger hw. Cell. 1997 Nov 28;91(5):695-704. doi: 10.1016/s0092-8674(00)80456-0. Cell. 1997. PMID: 9393862 Free article.

7

Crystal structure of the complex between VEGF and a receptor-blocking peptide.

Wiesmann C, Christinger HW, Cochran AG, Cunningham BC, Fairbrother WJ, Keenan CJ, Meng G, de Vos AM. Wiesmann C, et al. Among authors: christinger hw. Biochemistry. 1998 Dec 22;37(51):17765-72. doi: 10.1021/bi9819327. Biochemistry. 1998. PMID: 9922142

8

Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.

Chen Y, Wiesmann C, Fuh G, Li B, Christinger HW, McKay P, de Vos AM, Lowman HB. Chen Y, et al. Among authors: christinger hw. J Mol Biol. 1999 Nov 5;293(4):865-81. doi: 10.1006/jmbi.1999.3192. J Mol Biol. 1999. PMID: 10543973

9

Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site.

Fairbrother WJ, Christinger HW, Cochran AG, Fuh G, Keenan CJ, Quan C, Shriver SK, Tom JY, Wells JA, Cunningham BC. Fairbrother WJ, et al. Among authors: christinger hw. Biochemistry. 1998 Dec 22;37(51):17754-64. doi: 10.1021/bi981931e. Biochemistry. 1998. PMID: 9922141

10

Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states.

Starovasnik MA, Christinger HW, Wiesmann C, Champe MA, de Vos AM, Skelton NJ. Starovasnik MA, et al. Among authors: christinger hw. J Mol Biol. 1999 Oct 29;293(3):531-44. doi: 10.1006/jmbi.1999.3134. J Mol Biol. 1999. PMID: 10543948

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