Karpeisky A - Search Results

1

A core folding model for catalysis by the hammerhead ribozyme accounts for its extraordinary sensitivity to abasic mutations.

Peracchi A, Karpeisky A, Maloney L, Beigelman L, Herschlag D. Peracchi A, et al. Among authors: karpeisky a. Biochemistry. 1998 Oct 20;37(42):14765-75. doi: 10.1021/bi980867y. Biochemistry. 1998. PMID: 9778351

2

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance.

Beigelman L, McSwiggen JA, Draper KG, Gonzalez C, Jensen K, Karpeisky AM, Modak AS, Matulic-Adamic J, DiRenzo AB, Haeberli P, et al. Beigelman L, et al. Among authors: karpeisky am. J Biol Chem. 1995 Oct 27;270(43):25702-8. doi: 10.1074/jbc.270.43.25702. J Biol Chem. 1995. PMID: 7592749 Free article.

3

Chemically modified hammerhead ribozymes with improved catalytic rates.

Burgin AB Jr, Gonzalez C, Matulic-Adamic J, Karpeisky AM, Usman N, McSwiggen JA, Beigelman L. Burgin AB Jr, et al. Among authors: karpeisky am. Biochemistry. 1996 Nov 12;35(45):14090-7. doi: 10.1021/bi961264u. Biochemistry. 1996. PMID: 8916894

4

Functional groups on the cleavage site pyrimidine nucleotide are required for stabilization of the hammerhead transition state.

Baidya N, Ammons GE, Matulic-Adamic J, Karpeisky AM, Beigelman L, Uhlenbeck OC. Baidya N, et al. Among authors: karpeisky am. RNA. 1997 Oct;3(10):1135-42. RNA. 1997. PMID: 9326488 Free PMC article.

5

Synthesis of 2'-modified nucleotides and their incorporation into hammerhead ribozymes.

Beigelman L, Karpeisky A, Matulic-Adamic J, Haeberli P, Sweedler D, Usman N. Beigelman L, et al. Among authors: karpeisky a. Nucleic Acids Res. 1995 Nov 11;23(21):4434-42. doi: 10.1093/nar/23.21.4434. Nucleic Acids Res. 1995. PMID: 7501467 Free PMC article.

6

The structural basis of hammerhead ribozyme self-cleavage.

Murray JB, Terwey DP, Maloney L, Karpeisky A, Usman N, Beigelman L, Scott WG. Murray JB, et al. Among authors: karpeisky a. Cell. 1998 Mar 6;92(5):665-73. doi: 10.1016/s0092-8674(00)81134-4. Cell. 1998. PMID: 9506521 Free article.

7

Ribozyme catalysis from the major groove of group II intron domain 5.

Konforti BB, Abramovitz DL, Duarte CM, Karpeisky A, Beigelman L, Pyle AM. Konforti BB, et al. Among authors: karpeisky a. Mol Cell. 1998 Feb;1(3):433-41. doi: 10.1016/s1097-2765(00)80043-x. Mol Cell. 1998. PMID: 9660927 Free article.

8

Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosides.

Earnshaw DJ, Hamm ML, Piccirilli JA, Karpeisky A, Beigelman L, Ross BS, Manoharan M, Gait MJ. Earnshaw DJ, et al. Among authors: karpeisky a. Biochemistry. 2000 May 30;39(21):6410-21. doi: 10.1021/bi992974d. Biochemistry. 2000. PMID: 10828955

9

Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure.

Schmidt S, Beigelman L, Karpeisky A, Usman N, Sorensen US, Gait MJ. Schmidt S, et al. Among authors: karpeisky a. Nucleic Acids Res. 1996 Feb 15;24(4):573-81. doi: 10.1093/nar/24.4.573. Nucleic Acids Res. 1996. PMID: 8604296 Free PMC article.

10

Site-specific cross-linking of amino acids in the basic region of human immunodeficiency virus type 1 Tat peptide to chemically modified TAR RNA duplexes.

Farrow MA, Aboul-ela F, Owen D, Karpeisky A, Beigelman L, Gait MJ. Farrow MA, et al. Among authors: karpeisky a. Biochemistry. 1998 Mar 3;37(9):3096-108. doi: 10.1021/bi972695v. Biochemistry. 1998. PMID: 9485463

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