Shore JD - Search Results

1

Inhibitory mechanism of serpins: loop insertion forces acylation of plasminogen activator by plasminogen activator inhibitor-1.

Kvassman JO, Verhamme I, Shore JD. Kvassman JO, et al. Among authors: shore jd. Biochemistry. 1998 Nov 3;37(44):15491-502. doi: 10.1021/bi9814787. Biochemistry. 1998. PMID: 9799512

2

Mutation of the highly conserved tryptophan in the serpin breach region alters the inhibitory mechanism of plasminogen activator inhibitor-1.

Blouse GE, Perron MJ, Kvassman JO, Yunus S, Thompson JH, Betts RL, Lutter LC, Shore JD. Blouse GE, et al. Among authors: shore jd. Biochemistry. 2003 Oct 28;42(42):12260-72. doi: 10.1021/bi034737n. Biochemistry. 2003. PMID: 14567688

3

A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism.

Shore JD, Day DE, Francis-Chmura AM, Verhamme I, Kvassman J, Lawrence DA, Ginsburg D. Shore JD, et al. J Biol Chem. 1995 Mar 10;270(10):5395-8. doi: 10.1074/jbc.270.10.5395. J Biol Chem. 1995. PMID: 7890653 Free article.

4

Accelerated conversion of human plasminogen activator inhibitor-1 to its latent form by antibody binding.

Verhamme I, Kvassman JO, Day D, Debrock S, Vleugels N, Declerck PJ, Shore JD. Verhamme I, et al. Among authors: shore jd. J Biol Chem. 1999 Jun 18;274(25):17511-7. doi: 10.1074/jbc.274.25.17511. J Biol Chem. 1999. PMID: 10364183 Free article.

5

Resolution of Michaelis complex, acylation, and conformational change steps in the reactions of the serpin, plasminogen activator inhibitor-1, with tissue plasminogen activator and trypsin.

Olson ST, Swanson R, Day D, Verhamme I, Kvassman J, Shore JD. Olson ST, et al. Among authors: shore jd. Biochemistry. 2001 Oct 2;40(39):11742-56. doi: 10.1021/bi0107290. Biochemistry. 2001. PMID: 11570875

6

The acid stabilization of plasminogen activator inhibitor-1 depends on protonation of a single group that affects loop insertion into beta-sheet A.

Kvassman JO, Lawrence DA, Shore JD. Kvassman JO, et al. Among authors: shore jd. J Biol Chem. 1995 Nov 17;270(46):27942-7. doi: 10.1074/jbc.270.46.27942. J Biol Chem. 1995. PMID: 7499270 Free article.

7

A concerted structural transition in the plasminogen activator inhibitor-1 mechanism of inhibition.

Blouse GE, Perron MJ, Thompson JH, Day DE, Link CA, Shore JD. Blouse GE, et al. Among authors: shore jd. Biochemistry. 2002 Oct 8;41(40):11997-2009. doi: 10.1021/bi025967p. Biochemistry. 2002. PMID: 12356300

8

The use of fluorescent probes to characterize conformational changes in the interaction between vitronectin and plasminogen activator inhibitor-1.

Gibson A, Baburaj K, Day DE, Verhamme I, Shore JD, Peterson CB. Gibson A, et al. Among authors: shore jd. J Biol Chem. 1997 Feb 21;272(8):5112-21. doi: 10.1074/jbc.272.8.5112. J Biol Chem. 1997. PMID: 9030577 Free article.

9

Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.

Lawrence DA, Olson ST, Muhammad S, Day DE, Kvassman JO, Ginsburg D, Shore JD. Lawrence DA, et al. Among authors: shore jd. J Biol Chem. 2000 Feb 25;275(8):5839-44. doi: 10.1074/jbc.275.8.5839. J Biol Chem. 2000. PMID: 10681574 Free article.

10

Identification of tissue-type plasminogen activator-specific plasminogen activator inhibitor-1 mutants. Evidence that second sites of interaction contribute to target specificity.

Sherman PM, Lawrence DA, Verhamme IM, Paielli D, Shore JD, Ginsburg D. Sherman PM, et al. Among authors: shore jd. J Biol Chem. 1995 Apr 21;270(16):9301-6. doi: 10.1074/jbc.270.16.9301. J Biol Chem. 1995. PMID: 7721851 Free article.

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