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Oreganic acid, a potent inhibitor of ras farnesyl-protein transferase.
Silverman KC, Jayasuriya H, Cascales C, Vilella D, Bills GF, Jenkins RG, Singh SB, Lingham RB. Silverman KC, et al. Among authors: jayasuriya h. Biochem Biophys Res Commun. 1997 Mar 17;232(2):478-81. doi: 10.1006/bbrc.1997.6314. Biochem Biophys Res Commun. 1997. PMID: 9125205
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I.
Singh SB, Jayasuriya H, Salituro GM, Zink DL, Shafiee A, Heimbuch B, Silverman KC, Lingham RB, Genilloud O, Teran A, Vilella D, Felock P, Hazuda D. Singh SB, et al. Among authors: jayasuriya h. J Nat Prod. 2001 Jul;64(7):874-82. doi: 10.1021/np000632z. J Nat Prod. 2001. PMID: 11473415
Durhamycin A, a potent inhibitor of HIV Tat transactivation.
Jayasuriya H, Lingham RB, Graham P, Quamina D, Herranz L, Genilloud O, Gagliardi M, Danzeisen R, Tomassini JE, Zink DL, Guan Z, Singh SB. Jayasuriya H, et al. J Nat Prod. 2002 Aug;65(8):1091-5. doi: 10.1021/np010642f. J Nat Prod. 2002. PMID: 12193009
Inhibitors of farnesylation of Ras from a microbial natural products screening program.
Vilella D, Sánchez M, Platas G, Salazar O, Genilloud O, Royo I, Cascales C, Martín I, Díez T, Silverman KC, Lingham RB, Singh SB, Jayasuriya H, Peláez F. Vilella D, et al. Among authors: jayasuriya h. J Ind Microbiol Biotechnol. 2000 Dec;25(6):315-327. doi: 10.1038/sj.jim.7000085. J Ind Microbiol Biotechnol. 2000. PMID: 11320419
52 results