Fox T - Search Results

1

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase.

Fox T, Coll JT, Xie X, Ford PJ, Germann UA, Porter MD, Pazhanisamy S, Fleming MA, Galullo V, Su MS, Wilson KP. Fox T, et al. Protein Sci. 1998 Nov;7(11):2249-55. doi: 10.1002/pro.5560071102. Protein Sci. 1998. PMID: 9827991 Free PMC article.

2

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.

Xie X, Gu Y, Fox T, Coll JT, Fleming MA, Markland W, Caron PR, Wilson KP, Su MS. Xie X, et al. Among authors: fox t. Structure. 1998 Aug 15;6(8):983-91. doi: 10.1016/s0969-2126(98)00100-2. Structure. 1998. PMID: 9739089 Free article.

3

Inhibitors of p38 MAP kinase: therapeutic intervention in cytokine-mediated diseases.

Salituro FG, Germann UA, Wilson KP, Bemis GW, Fox T, Su MS. Salituro FG, et al. Among authors: fox t. Curr Med Chem. 1999 Sep;6(9):807-23. Curr Med Chem. 1999. PMID: 10495353 Review.

4

Kinetic mechanism and ATP-binding site reactivity of p38gamma MAP kinase.

Fox T, Fitzgibbon MJ, Fleming MA, Hsiao HM, Brummel CL, Su MS. Fox T, et al. FEBS Lett. 1999 Nov 19;461(3):323-8. doi: 10.1016/s0014-5793(99)01488-x. FEBS Lett. 1999. PMID: 10567720 Free article.

5

The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.

Bellon S, Fitzgibbon MJ, Fox T, Hsiao HM, Wilson KP. Bellon S, et al. Among authors: fox t. Structure. 1999 Sep 15;7(9):1057-65. doi: 10.1016/s0969-2126(99)80173-7. Structure. 1999. PMID: 10508788 Free article.

6

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity.

Wei Y, Fox T, Chambers SP, Sintchak J, Coll JT, Golec JM, Swenson L, Wilson KP, Charifson PS. Wei Y, et al. Among authors: fox t. Chem Biol. 2000 Jun;7(6):423-32. doi: 10.1016/s1074-5521(00)00123-x. Chem Biol. 2000. PMID: 10873833

7

Development of a protease production platform for structure-based drug design.

Fox T, Brennan D, Austen DA, Swalley SE, Coll JT, Raybuck SA, Chambers SP. Fox T, et al. Curr Protein Pept Sci. 2007 Oct;8(5):439-45. doi: 10.2174/138920307782411473. Curr Protein Pept Sci. 2007. PMID: 17979759 Review.

8

Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.

Fleming MA, Chambers SP, Connelly PR, Nimmesgern E, Fox T, Bruzzese FJ, Hoe ST, Fulghum JR, Livingston DJ, Stuver CM, Sintchak MD, Wilson KP, Thomson JA. Fleming MA, et al. Among authors: fox t. Biochemistry. 1996 Jun 4;35(22):6990-7. doi: 10.1021/bi9607416. Biochemistry. 1996. PMID: 8679523

9

Conformational changes and stabilization of inosine 5'-monophosphate dehydrogenase associated with ligand binding and inhibition by mycophenolic acid.

Nimmesgern E, Fox T, Fleming MA, Thomson JA. Nimmesgern E, et al. Among authors: fox t. J Biol Chem. 1996 Aug 9;271(32):19421-7. doi: 10.1074/jbc.271.32.19421. J Biol Chem. 1996. PMID: 8702630 Free article.

10

Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases.

Margolin N, Raybuck SA, Wilson KP, Chen W, Fox T, Gu Y, Livingston DJ. Margolin N, et al. Among authors: fox t. J Biol Chem. 1997 Mar 14;272(11):7223-8. doi: 10.1074/jbc.272.11.7223. J Biol Chem. 1997. PMID: 9054418 Free article.

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