Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways.
Barchowsky A, Roussel RR, Klei LR, James PE, Ganju N, Smith KR, Dudek EJ.
Barchowsky A, et al.
Toxicol Appl Pharmacol. 1999 Aug 15;159(1):65-75. doi: 10.1006/taap.1999.8723.
Toxicol Appl Pharmacol. 1999.
PMID: 10448126
Free article.
Exposure of endothelial cells to environmentally relevant concentrations of arsenic trioxide (arsenite) induces oxidant formation, activates the transcription factor NF-kappaB, and increases DNA synthesis (Barchowsky et al., Free Radic. Biol. Med. 21, 783-790, 1996). We sh …
Exposure of endothelial cells to environmentally relevant concentrations of arsenic trioxide (arsenite) induces oxidant formation, activates …