Patt WC - Search Results

1

Synthesis of novel substituted pyridines as inhibitors of endothelin converting enzyme-1 (ECE-1).

Massa MA, Patt WC, Ahn K, Sisneros AM, Herman SB, Doherty A. Massa MA, et al. Among authors: patt wc. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2117-22. doi: 10.1016/s0960-894x(98)00375-8. Bioorg Med Chem Lett. 1998. PMID: 9873497

2

Butenolide endothelin antagonists with improved aqueous solubility.

Patt WC, Cheng XM, Repine JT, Lee C, Reisdorph BR, Massa MA, Doherty AM, Welch KM, Bryant JW, Flynn MA, Walker DM, Schroeder RL, Haleen SJ, Keiser JA. Patt WC, et al. J Med Chem. 1999 Jun 17;42(12):2162-8. doi: 10.1021/jm980504w. J Med Chem. 1999. PMID: 10377221

3

Discovery of a novel series of orally active non-peptide endothelin-A (ETA) receptor-selective antagonists.

Doherty AM, Patt WC, Edmunds JJ, Berryman KA, Reisdorph BR, Plummer MS, Shahripour A, Lee C, Cheng XM, Walker DM, et al. Doherty AM, et al. Among authors: patt wc. J Med Chem. 1995 Apr 14;38(8):1259-63. doi: 10.1021/jm00008a002. J Med Chem. 1995. PMID: 7731010 No abstract available.

4

Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists.

Patt WC, Edmunds JJ, Repine JT, Berryman KA, Reisdorph BR, Lee C, Plummer MS, Shahripour A, Haleen SJ, Keiser JA, Flynn MA, Welch KM, Reynolds EE, Rubin R, Tobias B, Hallak H, Doherty AM. Patt WC, et al. J Med Chem. 1997 Mar 28;40(7):1063-74. doi: 10.1021/jm9606507. J Med Chem. 1997. PMID: 9089328

5

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors.

Patt WC, Hamilton HW, Taylor MD, Ryan MJ, Taylor DG Jr, Connolly CJ, Doherty AM, Klutchko SR, Sircar I, Steinbaugh BA, et al. Patt WC, et al. J Med Chem. 1992 Jul 10;35(14):2562-72. doi: 10.1021/jm00092a006. J Med Chem. 1992. PMID: 1635057

6

Inhibitors of lipoprotein(a) assembly.

Sexton KE, Lee HT, Massa M, Padia J, Patt WC, Liao P, Pontrello JK, Roth BD, Spahr MA, Ramharack R. Sexton KE, et al. Among authors: patt wc. Bioorg Med Chem. 2003 Nov 3;11(22):4827-45. doi: 10.1016/j.bmc.2002.04.001. Bioorg Med Chem. 2003. PMID: 14556799

7

Structure-activity relationships of a novel series of orally active nonpeptide ETA and ETA/B endothelin receptor-selective antagonists.

Doherty AM, Patt WC, Repine J, Edmunds JJ, Berryman KA, Reisdorph BR, Walker DM, Haleen SJ, Keiser JA, Flynn MA, et al. Doherty AM, et al. Among authors: patt wc. J Cardiovasc Pharmacol. 1995;26 Suppl 3:S358-61. J Cardiovasc Pharmacol. 1995. PMID: 8587414

8

N6-substituted adenosine receptor agonists: potential antihypertensive agents.

Trivedi BK, Blankley CJ, Bristol JA, Hamilton HW, Patt WC, Kramer WJ, Johnson SA, Bruns RF, Cohen DM, Ryan MJ. Trivedi BK, et al. Among authors: patt wc. J Med Chem. 1991 Mar;34(3):1043-9. doi: 10.1021/jm00107a025. J Med Chem. 1991. PMID: 2002448

9

N6-bicycloalkyladenosines with unusually high potency and selectivity for the adenosine A1 receptor.

Trivedi BK, Bridges AJ, Patt WC, Priebe SR, Bruns RF. Trivedi BK, et al. Among authors: patt wc. J Med Chem. 1989 Jan;32(1):8-11. doi: 10.1021/jm00121a002. J Med Chem. 1989. PMID: 2909748 No abstract available.

10

Characterization of [125I]-PD164333, an ETA selective non-peptide radiolabelled antagonist, in normal and diseased human tissues.

Davenport AP, Kuc RE, Ashby MJ, Patt WC, Doherty AM. Davenport AP, et al. Among authors: patt wc. Br J Pharmacol. 1998 Jan;123(2):223-30. doi: 10.1038/sj.bjp.0701597. Br J Pharmacol. 1998. PMID: 9489609 Free PMC article.

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