Jansen G - Search Results

1

Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.

Rots MG, Pieters R, Kaspers GJ, van Zantwijk CH, Noordhuis P, Mauritz R, Veerman AJ, Jansen G, Peters GJ. Rots MG, et al. Among authors: jansen g. Blood. 1999 Feb 1;93(3):1067-74. Blood. 1999. PMID: 9920857 Free article.

2

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.

Westerhof GR, Jansen G, van Emmerik N, Kathmann I, Rijksen G, Jackman AL, Schornagel JH. Westerhof GR, et al. Among authors: jansen g. Cancer Res. 1991 Oct 15;51(20):5507-13. Cancer Res. 1991. PMID: 1655252

L1210-B73 cells, variants of L1210 cells grown in medium containing nanomolar concentrations of folates, express a membrane associated folate binding protein (mFBP) in addition to the classical reduced folate/methotrexate carrier (RF/MTX-carrier) present in L1210 cells grown in s …

L1210-B73 cells, variants of L1210 cells grown in medium containing nanomolar concentrations of folates, express a membrane associated folat …

3

Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.

Braakhuis BJ, Jansen G, Noordhuis P, Kegel A, Peters GJ. Braakhuis BJ, et al. Among authors: jansen g. Biochem Pharmacol. 1993 Dec 14;46(12):2155-61. doi: 10.1016/0006-2952(93)90604-u. Biochem Pharmacol. 1993. PMID: 7506025

4

Leucovorin rescue of human cancer and bone marrow cells following edatrexate or methotrexate.

Jolivet J, Jansen G, Peters GJ, Pinard MF, Schornagel JH. Jolivet J, et al. Among authors: jansen g. Biochem Pharmacol. 1994 Feb 11;47(4):659-65. doi: 10.1016/0006-2952(94)90128-7. Biochem Pharmacol. 1994. PMID: 7510479

5

Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.

Westerhof GR, Rijnboutt S, Schornagel JH, Pinedo HM, Peters GJ, Jansen G. Westerhof GR, et al. Among authors: jansen g. Cancer Res. 1995 Sep 1;55(17):3795-802. Cancer Res. 1995. PMID: 7641196

6

Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.

Braakhuis BJ, Jansen G, Peters GJ. Braakhuis BJ, et al. Among authors: jansen g. Adv Exp Med Biol. 1993;338:671-4. doi: 10.1007/978-1-4615-2960-6_139. Adv Exp Med Biol. 1993. PMID: 8304205 No abstract available.

7

Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.

van Triest B, Pinedo HM, Telleman F, van der Wilt CL, Jansen G, Peters GJ. van Triest B, et al. Among authors: jansen g. Biochem Pharmacol. 1997 Jun 15;53(12):1855-66. doi: 10.1016/s0006-2952(97)82448-3. Biochem Pharmacol. 1997. PMID: 9256160

8

Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.

Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ. Jansen G, et al. Adv Enzyme Regul. 1997;37:59-76. doi: 10.1016/s0065-2571(96)00012-x. Adv Enzyme Regul. 1997. PMID: 9381986

9

Determinants of the therapeutic efficacy of thymidylate synthase inhibitors.

Peters GJ, Kuiper CM, van Triest B, Backus H, van der Wilt CL, van Laar JA, Jansen G, van Groeningen CJ, Pinedo HM. Peters GJ, et al. Among authors: jansen g. Adv Exp Med Biol. 1998;431:699-704. doi: 10.1007/978-1-4615-5381-6_135. Adv Exp Med Biol. 1998. PMID: 9598155 No abstract available.

10

Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.

Mauritz R, Bekkenk MW, Rots MG, Pieters R, Mini E, van Zantwijk CH, Veerman AJ, Peters GJ, Jansen G. Mauritz R, et al. Among authors: jansen g. Clin Cancer Res. 1998 Oct;4(10):2399-410. Clin Cancer Res. 1998. PMID: 9796971

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