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Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury.
Tsung A, Zheng N, Jeyabalan G, Izuishi K, Klune JR, Geller DA, Lotze MT, Lu L, Billiar TR. Tsung A, et al. J Leukoc Biol. 2007 Jan;81(1):119-28. doi: 10.1189/jlb.0706468. Epub 2006 Oct 24. J Leukoc Biol. 2007. PMID: 17062605
Here, we demonstrate that increasing dendritic cell (DC) numbers enhance inflammation and organ injury after hepatic I/R. High-mobility group box 1 (HMGB1), a NF released by necrotic cells or secreted by stimulated cells, is one of a number of ligands promoting TLR4 reacti …
Here, we demonstrate that increasing dendritic cell (DC) numbers enhance inflammation and organ injury after hepatic I/R. High-mobility grou …
Cytolytic cells induce HMGB1 release from melanoma cell lines.
Ito N, DeMarco RA, Mailliard RB, Han J, Rabinowich H, Kalinski P, Stolz DB, Zeh HJ 3rd, Lotze MT. Ito N, et al. J Leukoc Biol. 2007 Jan;81(1):75-83. doi: 10.1189/jlb.0306169. Epub 2006 Sep 12. J Leukoc Biol. 2007. PMID: 16968820
High mobility group box 1 (HMGB1) is one of the recently defined damage-associated molecular pattern molecules, passively released from necrotic cells and secreted by activated macrophage/monocytes. ...
High mobility group box 1 (HMGB1) is one of the recently defined damage-associated molecular pattern molecules, passively released fr …