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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Nature. 2012 Jun 28;486(7404):490-5. doi: 10.1038/nature11163.
Nature. 2012.
PMID: 22722868
Free PMC article.
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA.
Lamming DW, et al.
Science. 2012 Mar 30;335(6076):1638-43. doi: 10.1126/science.1215135.
Science. 2012.
PMID: 22461615
Free PMC article.
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