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Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Cui F, Pan Q, Wang S, Zhao F, Wang R, Zhang T, Song Y, He J, Zhang H, Weng Q, Jin Y, Xia W, Li Y, Yang GY, De Vos WH, Timmermans JP, Xu S, Tang Y, Sheng X. Cui F, et al. Adv Sci (Weinh). 2021 Dec;8(23):e2102686. doi: 10.1002/advs.202102686. Epub 2021 Oct 28. Adv Sci (Weinh). 2021. PMID: 34713618 Free PMC article.
Mechanistically, 4HBP exposure activates protein kinase R-like ER kinase (PERK) signaling, which induces CHOP, inhibits IkappaB translation, and transactivates p65, thereby promoting inflammation and apoptosis on multiple levels. ...
Mechanistically, 4HBP exposure activates protein kinase R-like ER kinase (PERK) signaling, which induces CHOP, inhibits IkappaB trans …
Dl-3-n-Butylphthalide Reduced Neuroinflammation by Inhibiting Inflammasome in Microglia in Mice after Middle Cerebral Artery Occlusion.
Liu M, Zheng H, Liu Z, Guo Y, Wang S, Tang Y, Tian H, Zhang Z, Yang G. Liu M, et al. Life (Basel). 2022 Aug 16;12(8):1244. doi: 10.3390/life12081244. Life (Basel). 2022. PMID: 36013423 Free PMC article.
The inflammatory response is one of the key events in cerebral ischemia, causing secondary brain injury and neuronal death. Studies have shown that the NLRP3 inflammasome is a key factor in initiating the inflammatory response and that Dl-3-n-butylphthalide (NBP) ca …
The inflammatory response is one of the key events in cerebral ischemia, causing secondary brain injury and neuronal death. Studies h …