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Multi-omics panoramic analysis of HBV integration, transcriptional regulation, and epigenetic modifications in PLC/PRF/5 cell line.
Guan G, Abulaiti A, Qu C, Chen CC, Gu Z, Yang J, Zhang T, Chen X, Zhou Z, Lu F, Chen X. Guan G, et al. J Med Virol. 2024 Apr;96(4):e29614. doi: 10.1002/jmv.29614. J Med Virol. 2024. PMID: 38647071
Analysis of WGBS data showed that the methylation intensity of integrated HBV DNA was highly negatively correlated with its transcription level (r = -0.8929, p = 0.0123). After AzaD treatment, the transcription level of integrated HBV DNA significantly increased, especiall …
Analysis of WGBS data showed that the methylation intensity of integrated HBV DNA was highly negatively correlated with its transcription le …