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Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes.
Johnson BB, Cosson MV, Tsansizi LI, Holmes TL, Gilmore T, Hampton K, Song OR, Vo NTN, Nasir A, Chabronova A, Denning C, Peffers MJ, Merry CLR, Whitelock J, Troeberg L, Rushworth SA, Bernardo AS, Smith JGW. Johnson BB, et al. Cell Rep. 2024 Jan 23;43(1):113668. doi: 10.1016/j.celrep.2023.113668. Epub 2024 Jan 9. Cell Rep. 2024. PMID: 38198277 Free article.
Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells.
Dark N, Cosson MV, Tsansizi LI, Owen TJ, Ferraro E, Francis AJ, Tsai S, Bouissou C, Weston A, Collinson L, Abi-Gerges N, Miller PE, MacLeod KT, Ehler E, Mitter R, Harding SE, Smith JC, Bernardo AS. Dark N, et al. Cell Rep Methods. 2023 Apr 24;3(4):100456. doi: 10.1016/j.crmeth.2023.100456. eCollection 2023 Apr 24. Cell Rep Methods. 2023. PMID: 37159667 Free PMC article.
Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Pitrez PR, Estronca L, Monteiro LM, Colell G, Vazão H, Santinha D, Harhouri K, Thornton D, Navarro C, Egesipe AL, Carvalho T, Dos Santos RL, Lévy N, Smith JC, de Magalhães JP, Ori A, Bernardo A, De Sandre-Giovannoli A, Nissan X, Rosell A, Ferreira L. Pitrez PR, et al. Nat Commun. 2020 Aug 17;11(1):4110. doi: 10.1038/s41467-020-17901-2. Nat Commun. 2020. PMID: 32807790 Free PMC article.