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Page 1
Lymphangiogenic factors, mechanisms, and applications.
Zheng W, Aspelund A, Alitalo K. Zheng W, et al. J Clin Invest. 2014 Mar;124(3):878-87. doi: 10.1172/JCI71603. Epub 2014 Mar 3. J Clin Invest. 2014. PMID: 24590272 Free PMC article. Review.
VEGFR3 does not sustain retinal angiogenesis without VEGFR2.
Zarkada G, Heinolainen K, Makinen T, Kubota Y, Alitalo K. Zarkada G, et al. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):761-6. doi: 10.1073/pnas.1423278112. Epub 2015 Jan 5. Proc Natl Acad Sci U S A. 2015. PMID: 25561555 Free PMC article.
Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Korhonen EA, Lampinen A, Giri H, Anisimov A, Kim M, Allen B, Fang S, D'Amico G, Sipilä TJ, Lohela M, Strandin T, Vaheri A, Ylä-Herttuala S, Koh GY, McDonald DM, Alitalo K, Saharinen P. Korhonen EA, et al. J Clin Invest. 2016 Sep 1;126(9):3495-510. doi: 10.1172/JCI84923. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548530 Free PMC article.
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation.
Leppänen VM, Tvorogov D, Kisko K, Prota AE, Jeltsch M, Anisimov A, Markovic-Mueller S, Stuttfeld E, Goldie KN, Ballmer-Hofer K, Alitalo K. Leppänen VM, et al. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):12960-5. doi: 10.1073/pnas.1301415110. Epub 2013 Jul 22. Proc Natl Acad Sci U S A. 2013. PMID: 23878260 Free PMC article.
The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.
Aspelund A, Tammela T, Antila S, Nurmi H, Leppänen VM, Zarkada G, Stanczuk L, Francois M, Mäkinen T, Saharinen P, Immonen I, Alitalo K. Aspelund A, et al. J Clin Invest. 2014 Sep;124(9):3975-86. doi: 10.1172/JCI75395. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061878 Free PMC article.
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.
Kim M, Allen B, Korhonen EA, Nitschké M, Yang HW, Baluk P, Saharinen P, Alitalo K, Daly C, Thurston G, McDonald DM. Kim M, et al. J Clin Invest. 2016 Sep 1;126(9):3511-25. doi: 10.1172/JCI84871. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548529 Free PMC article.
20 results