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A suitable model to investigate acute neurological consequences of coronavirus infection.
Pimenta J, Da Silva Oliveira B, Lima ALD, Machado CA, De Souza Barbosa Lacerda L, Rossi L, Queiroz-Junior CM, De Souza-Costa LP, Andrade ACSP, Gonçalves MR, Mota B, Marim FM, Aguiar RS, Guimarães PPG, Teixeira AL, Vieira LB, Guatimosim C, Teixeira MM, De Miranda AS, Costa VV. Pimenta J, et al. Inflamm Res. 2023 Nov;72(10-11):2073-2088. doi: 10.1007/s00011-023-01798-w. Epub 2023 Oct 14. Inflamm Res. 2023. PMID: 37837557
Effects of a pro-resolving drug in COVID-19: preclinical studies to a randomized, placebo-controlled, phase Ib/IIa trial in hospitalized patients.
Almeida PRJ, Periard AM, Tana FL, Avila RE, Milhorato LB, Alcantara KMM, Resende CB, Serufo AV, Santos FR, Teixeira DC, Queiroz-Junior CM, Fonseca TCM, Silva BLV, Costa VV, Souza RP, Perretti M, Jonassen TEN, Teixeira MM. Almeida PRJ, et al. Br J Pharmacol. 2024 Dec;181(23):4750-4765. doi: 10.1111/bph.17322. Epub 2024 Aug 19. Br J Pharmacol. 2024. PMID: 39159951 Clinical Trial.
Intranasal liposomal angiotensin-(1-7) administration reduces inflammation and viral load in the lungs during SARS-CoV-2 infection in K18-hACE2 transgenic mice.
Mendes S, Guimarães LC, Costa PAC, Fernandez CC, Figueiredo MM, Teixeira MM, Dos Santos RAS, Guimarães PPG, Frézard F. Mendes S, et al. Antimicrob Agents Chemother. 2024 Dec 5;68(12):e0083524. doi: 10.1128/aac.00835-24. Epub 2024 Oct 29. Antimicrob Agents Chemother. 2024. PMID: 39470198 Free article.