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Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer.
Wang M, Topalovski M, Toombs JE, Wright CM, Moore ZR, Boothman DA, Yanagisawa H, Wang H, Witkiewicz A, Castrillon DH, Brekken RA. Wang M, et al. Cancer Res. 2015 Dec 1;75(23):5058-69. doi: 10.1158/0008-5472.CAN-15-0744. Epub 2015 Nov 17. Cancer Res. 2015. PMID: 26577699 Free PMC article.
Perifosine as a potential novel anti-telomerase therapy.
Holohan B, Hagiopian MM, Lai TP, Huang E, Friedman DR, Wright WE, Shay JW. Holohan B, et al. Oncotarget. 2015 Sep 8;6(26):21816-26. doi: 10.18632/oncotarget.5200. Oncotarget. 2015. PMID: 26307677 Free PMC article.
Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.
Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK. Rogers JL, et al. J Med Chem. 2013 Feb 28;56(4):1739-47. doi: 10.1021/jm301847z. Epub 2013 Feb 18. J Med Chem. 2013. PMID: 23363003 Free PMC article.