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Lipid-conjugated Smac analogues.
Micewicz ED, Ratikan JA, Waring AJ, Whitelegge JP, McBride WH, Ruchala P. Micewicz ED, et al. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4419-27. doi: 10.1016/j.bmcl.2015.09.017. Epub 2015 Sep 8. Bioorg Med Chem Lett. 2015. PMID: 26384289 Free PMC article.
Small lipidated anti-obesity compounds derived from neuromedin U.
Micewicz ED, Bahattab OS, Willars GB, Waring AJ, Navab M, Whitelegge JP, McBride WH, Ruchala P. Micewicz ED, et al. Eur J Med Chem. 2015 Aug 28;101:616-26. doi: 10.1016/j.ejmech.2015.07.020. Epub 2015 Jul 14. Eur J Med Chem. 2015. PMID: 26204509 Free PMC article.
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization.
Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, Reue K, Spencer MJ, Newgard CB, Tontonoz P. Chao LC, et al. J Lipid Res. 2012 Dec;53(12):2610-9. doi: 10.1194/jlr.M029355. Epub 2012 Oct 1. J Lipid Res. 2012. PMID: 23028113 Free PMC article.