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Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors.
Flores-Bellver M, Mighty J, Aparicio-Domingo S, Li KV, Shi C, Zhou J, Cobb H, McGrath P, Michelis G, Lenhart P, Bilousova G, Heissel S, Rudy MJ, Coughlan C, Goodspeed AE, Becerra SP, Redenti S, Canto-Soler MV. Flores-Bellver M, et al. J Extracell Vesicles. 2021 Nov;10(13):e12165. doi: 10.1002/jev2.12165. J Extracell Vesicles. 2021. PMID: 34750957 Free PMC article.
Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitor cells.
Zhou J, Flores-Bellver M, Pan J, Benito-Martin A, Shi C, Onwumere O, Mighty J, Qian J, Zhong X, Hogue T, Amponsah-Antwi B, Einbond L, Gharbaran R, Wu H, Chen BJ, Zheng Z, Tchaikovskaya T, Zhang X, Peinado H, Canto-Soler MV, Redenti S. Zhou J, et al. Sci Rep. 2021 Oct 26;11(1):21128. doi: 10.1038/s41598-021-00542-w. Sci Rep. 2021. PMID: 34702879 Free PMC article.
Diminazene aceturate-induced cytotoxicity is associated with the deregulation of cell cycle signaling and downregulation of oncogenes Furin, c-MYC, and FOXM1 in human cervical carcinoma Hela cells.
Gharbaran R, Sayibou Z, Atamturktur S, Ofosu-Mensah JJ, Soto J, Boodhan N, Kolya S, Onwumere O, Chang L, Somenarain L, Redenti S. Gharbaran R, et al. J Biochem Mol Toxicol. 2024 Jan;38(1):e23527. doi: 10.1002/jbt.23527. Epub 2023 Sep 8. J Biochem Mol Toxicol. 2024. PMID: 37681557