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Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance.
Neurobiol Dis. 2016 Jan;85:111-121. doi: 10.1016/j.nbd.2015.10.019. Epub 2015 Oct 22.
Neurobiol Dis. 2016.
PMID: 26525100
Free PMC article.
Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.
Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ.
Li S, et al.
J Neurosci. 2011 May 4;31(18):6627-38. doi: 10.1523/JNEUROSCI.0203-11.2011.
J Neurosci. 2011.
PMID: 21543591
Free PMC article.
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Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.
Li S, Jin M, Zhang D, Yang T, Koeglsperger T, Fu H, Selkoe DJ.
Li S, et al.
Neuron. 2013 Mar 6;77(5):929-41. doi: 10.1016/j.neuron.2012.12.040.
Neuron. 2013.
PMID: 23473322
Free PMC article.
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