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The single subunit transmembrane E3 ligase gene related to anergy in lymphocytes (GRAIL) captures and then ubiquitinates transmembrane proteins across the cell membrane.
J Biol Chem. 2008 Oct 17;283(42):28497-505. doi: 10.1074/jbc.M805092200. Epub 2008 Aug 18.
J Biol Chem. 2008.
PMID: 18713730
Free PMC article.
Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy.
Lineberry NB, Su LL, Lin JT, Coffey GP, Seroogy CM, Fathman CG.
Lineberry NB, et al.
J Immunol. 2008 Aug 1;181(3):1622-6. doi: 10.4049/jimmunol.181.3.1622.
J Immunol. 2008.
PMID: 18641297
Free PMC article.
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