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Page 1
Control of apoptosis in hematopoietic cells by the Bcl-2 family of proteins.
Adams JM, Huang DC, Puthalakath H, Bouillet P, Vairo G, Moriishi K, Hausmann G, O'Reilly L, Newton K, Ogilvy S, Bath ML, Print CG, Harris AW, Strasser A, Cory S. Adams JM, et al. Cold Spring Harb Symp Quant Biol. 1999;64:351-8. doi: 10.1101/sqb.1999.64.351. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232307 Review. No abstract available.
ER stress triggers apoptosis by activating BH3-only protein Bim.
Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin J, Motoyama N, Gotoh T, Akira S, Bouillet P, Strasser A. Puthalakath H, et al. Cell. 2007 Jun 29;129(7):1337-49. doi: 10.1016/j.cell.2007.04.027. Cell. 2007. PMID: 17604722 Free article.
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.
Kuroda J, Puthalakath H, Cragg MS, Kelly PN, Bouillet P, Huang DC, Kimura S, Ottmann OG, Druker BJ, Villunger A, Roberts AW, Strasser A. Kuroda J, et al. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14907-12. doi: 10.1073/pnas.0606176103. Epub 2006 Sep 22. Proc Natl Acad Sci U S A. 2006. PMID: 16997913 Free PMC article.
XIAP discriminates between type I and type II FAS-induced apoptosis.
Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T. Jost PJ, et al. Nature. 2009 Aug 20;460(7258):1035-9. doi: 10.1038/nature08229. Epub 2009 Jul 22. Nature. 2009. PMID: 19626005 Free PMC article.
36 results