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Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea.
Peiper AM, Morales Aparicio J, Hu Z, Phophi L, Helm EW, Rubinstein RJ, Phillips M, Williams CG, Subramanian S, Cross M, Iyer N, Nguyen Q, Newsome R, Jobin C, Langel SN, Bucardo F, Becker-Dreps S, Tan XD, Dawson PA, Karst SM. Peiper AM, et al. Cell Host Microbe. 2024 Sep 11;32(9):1488-1501.e5. doi: 10.1016/j.chom.2024.08.003. Epub 2024 Aug 29. Cell Host Microbe. 2024. PMID: 39214086
Murine Norovirus: Additional Protocols for Basic and Antiviral Studies.
Wobus CE, Peiper AM, McSweeney AM, Young VL, Chaika M, Lane MS, Lingemann M, Deerain JM, Strine MS, Alfajaro MM, Helm EW, Karst SM, Mackenzie JM, Taube S, Ward VK, Wilen CB. Wobus CE, et al. Curr Protoc. 2023 Jul;3(7):e828. doi: 10.1002/cpz1.828. Curr Protoc. 2023. PMID: 37478303 Free PMC article.
Environmentally-triggered contraction of the norovirus virion determines diarrheagenic potential.
Helm EW, Peiper AM, Phillips M, Williams CG, Sherman MB, Kelley T, Smith HQ, Jacobs SO, Shah D, Tatum SM, Iyer N, Grodzki M, Morales Aparicio JC, Kennedy EA, Manzi MS, Baldridge MT, Smith TJ, Karst SM. Helm EW, et al. Front Immunol. 2022 Nov 1;13:1043746. doi: 10.3389/fimmu.2022.1043746. eCollection 2022. Front Immunol. 2022. PMID: 36389732 Free PMC article.