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MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.
Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV. Altman BJ, et al. Cell Metab. 2015 Dec 1;22(6):1009-19. doi: 10.1016/j.cmet.2015.09.003. Epub 2015 Sep 17. Cell Metab. 2015. PMID: 26387865 Free PMC article.
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV. Walton ZE, et al. Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31. Cell. 2018. PMID: 29861175 Free PMC article.
MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis.
Cazarin J, DeRollo RE, Ahmad Shahidan SNAB, Burchett JB, Mwangi D, Krishnaiah S, Hsieh AL, Walton ZE, Brooks R, Mello SS, Weljie AM, Dang CV, Altman BJ. Cazarin J, et al. bioRxiv [Preprint]. 2023 Aug 8:2023.01.03.522637. doi: 10.1101/2023.01.03.522637. bioRxiv. 2023. Update in: PLoS Genet. 2023 Aug 28;19(8):e1010904. doi: 10.1371/journal.pgen.1010904 PMID: 36711638 Free PMC article. Updated. Preprint.