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A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.
Park RJ, Wang T, Koundakjian D, Hultquist JF, Lamothe-Molina P, Monel B, Schumann K, Yu H, Krupzcak KM, Garcia-Beltran W, Piechocka-Trocha A, Krogan NJ, Marson A, Sabatini DM, Lander ES, Hacohen N, Walker BD. Park RJ, et al. Nat Genet. 2017 Feb;49(2):193-203. doi: 10.1038/ng.3741. Epub 2016 Dec 19. Nat Genet. 2017. PMID: 27992415 Free PMC article.
Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.
Garcia-Beltran WF, Hölzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, Altfeld M. Garcia-Beltran WF, et al. Nat Immunol. 2016 Sep;17(9):1067-74. doi: 10.1038/ni.3513. Epub 2016 Jul 25. Nat Immunol. 2016. PMID: 27455421 Free PMC article.
Innate immune reconstitution with suppression of HIV-1.
Scully EP, Lockhart A, Garcia-Beltran W, Palmer CD, Musante C, Rosenberg E, Allen TM, Chang JJ, Bosch RJ, Altfeld M. Scully EP, et al. JCI Insight. 2016 Mar 17;1(3):e85433. doi: 10.1172/jci.insight.85433. JCI Insight. 2016. PMID: 27158667 Free PMC article.
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44.
Niehrs A, Garcia-Beltran WF, Norman PJ, Watson GM, Hölzemer A, Chapel A, Richert L, Pommerening-Röser A, Körner C, Ozawa M, Martrus G, Rossjohn J, Lee JH, Berry R, Carrington M, Altfeld M. Niehrs A, et al. Nat Immunol. 2019 Sep;20(9):1129-1137. doi: 10.1038/s41590-019-0448-4. Epub 2019 Jul 29. Nat Immunol. 2019. PMID: 31358998 Free PMC article.
Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection.
Garcia-Beltran WF, Claiborne DT, Maldini CR, Phelps M, Vrbanac V, Karpel ME, Krupp KL, Power KA, Boutwell CL, Balazs AB, Tager AM, Altfeld M, Allen TM. Garcia-Beltran WF, et al. Front Immunol. 2021 May 26;12:667393. doi: 10.3389/fimmu.2021.667393. eCollection 2021. Front Immunol. 2021. PMID: 34122425 Free PMC article.
11 results