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2019 4
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2025 4

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Page 1
CD137 (4-1BB) and T-Lymphocyte Exhaustion.
Molero-Glez P, Azpilikueta A, Mosteo L, Glez-Vaz J, Palencia B, Melero I. Molero-Glez P, et al. Clin Cancer Res. 2024 Sep 13;30(18):3971-3973. doi: 10.1158/1078-0432.CCR-24-1568. Clin Cancer Res. 2024. PMID: 39120463
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression.
Molina O, Ortega-Sabater C, Thampi N, Fernández-Fuentes N, Guerrero-Murillo M, Martínez-Moreno A, Vinyoles M, Velasco-Hernández T, Bueno C, Trincado JL, Granada I, Campos D, Giménez C, Boer JM, den Boer ML, Calvo GF, Camós M, Fuster JL, Velasco P, Ballerini P, Locatelli F, Mullighan CG, Spierings DCJ, Foijer F, Pérez-García VM, Menéndez P. Molina O, et al. EMBO Mol Med. 2024 Jan;16(1):64-92. doi: 10.1038/s44321-023-00006-w. Epub 2023 Dec 15. EMBO Mol Med. 2024. PMID: 38177531 Free PMC article.
PD-1/LAG-3 co-signaling profiling uncovers CBL ubiquitin ligases as key immunotherapy targets.
Chocarro L, Blanco E, Fernandez-Rubio L, Garnica M, Zuazo M, Garcia MJ, Bocanegra A, Echaide M, Johnston C, Edwards CJ, Legg J, Pierce AJ, Arasanz H, Fernandez-Hinojal G, Vera R, Ausin K, Santamaria E, Fernandez-Irigoyen J, Kochan G, Escors D. Chocarro L, et al. EMBO Mol Med. 2024 Aug;16(8):1791-1816. doi: 10.1038/s44321-024-00098-y. Epub 2024 Jul 19. EMBO Mol Med. 2024. PMID: 39030301 Free PMC article.
TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.
Priego N, de Pablos-Aragoneses A, Perea-García M, Pieri V, Hernández-Oliver C, Álvaro-Espinosa L, Rojas A, Sánchez O, Steindl A, Caleiras E, García F, García-Martín S, Graña-Castro O, García-Mulero S, Serrano D, Velasco-Beltrán P, Jiménez-Lasheras B, Egia-Mendikute L, Rupp L, Stammberger A, Meinhardt M, Chaachou-Charradi A, Martínez-Saez E, Bertero L, Cassoni P, Mangherini L, Pellerino A, Rudà R, Soffietti R, Al-Shahrour F, Saftig P, Sanz-Pamplona R, Schmitz M, Crocker SJ, Calvo A, Palazón A; RENACER; Valiente M. Priego N, et al. Cancer Discov. 2025 Jan 13;15(1):179-201. doi: 10.1158/2159-8290.CD-24-0134. Cancer Discov. 2025. PMID: 39354883 Free PMC article.
Cyclophilin D plays a critical role in the survival of senescent cells.
Protasoni M, López-Polo V, Stephan-Otto Attolini C, Brandariz J, Herranz N, Mateo J, Ruiz S, Fernandez-Capetillo O, Kovatcheva M, Serrano M. Protasoni M, et al. EMBO J. 2024 Dec;43(23):5972-6000. doi: 10.1038/s44318-024-00259-2. Epub 2024 Oct 24. EMBO J. 2024. PMID: 39448884 Free PMC article.
Nonviral CRISPR/Cas9 mutagenesis for streamlined generation of mouse lung cancer models.
Lara-Sáez I, Mencía Á, Recuero E, Li Y, García M, Oteo M, Gallego MI, Enguita AB, de Prado-Verdún D, A S, Wang W, García-Escudero R, Murillas R, Santos M. Lara-Sáez I, et al. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2322917121. doi: 10.1073/pnas.2322917121. Epub 2024 Jul 3. Proc Natl Acad Sci U S A. 2024. PMID: 38959035 Free PMC article.
Strategies to enhance the response of liver cancer to pharmacological treatments.
Marin JJG, Macias RIR, Asensio M, Romero MR, Temprano AG, Pereira OR, Jimenez S, Mauriz JL, Di Giacomo S, Avila MA, Efferth T, Briz O. Marin JJG, et al. Am J Physiol Cell Physiol. 2024 Jul 1;327(1):C11-C33. doi: 10.1152/ajpcell.00176.2024. Epub 2024 May 6. Am J Physiol Cell Physiol. 2024. PMID: 38708523 Review.
Short-Chain Fatty Acid Production by Gut Microbiota Predicts Treatment Response in Multiple Myeloma.
Rodríguez-García A, Arroyo A, García-Vicente R, Morales ML, Gómez-Gordo R, Justo P, Cuéllar C, Sánchez-Pina J, López N, Alonso R, Puig N, Mateos MV, Ayala R, Gómez-Garre D, Martínez-López J, Linares M. Rodríguez-García A, et al. Clin Cancer Res. 2024 Feb 16;30(4):904-917. doi: 10.1158/1078-0432.CCR-23-0195. Clin Cancer Res. 2024. PMID: 38109212 Free PMC article.
Biomarkers of Efficacy and Safety of the Academic BCMA-CART ARI0002h for the Treatment of Refractory Multiple Myeloma.
Oliver-Caldes A, Español-Rego M, Zabaleta A, González-Calle V, Navarro-Velázquez S, Inogés S, de Cerio AL, Cabañas V, López-Muñoz N, Rodríguez-Otero P, Reguera JL, Moreno DF, Martínez-Cibrian N, López-Corral L, Pérez-Amill L, Martin-Antonio B, Rosiñol L, Cid J, Tovar N, Sáez-Peñataro J, López-Parra M, Olesti E, Guillén E, Varea S, Rodríguez-Lobato LG, Battram AM, González MS, Sánchez-Salinas A, González-Navarro A, Ortiz-Maldonado V, Delgado J, Prósper F, Juan M, Martínez-López J, Moraleda JM, Mateos MV, Urbano-Ispizua Á, Paiva B, Pascal M, Fernández de Larrea C. Oliver-Caldes A, et al. Clin Cancer Res. 2024 May 15;30(10):2085-2096. doi: 10.1158/1078-0432.CCR-23-3759. Clin Cancer Res. 2024. PMID: 38466644
34 results