G0400848/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2006	1
2007	3
2008	2
2009	2
2010	1
2011	2
2012	1
2013	3
2015	2
2017	1
2019	4
2020	2
2021	3
2023	1
2025	0

1

The Molecular Basis of Antibiotic Action and Resistance.

Maxwell A, Dowson CG, Spencer J. Maxwell A, et al. J Mol Biol. 2019 Aug 23;431(18):3367-3369. doi: 10.1016/j.jmb.2019.06.018. Epub 2019 Jun 29. J Mol Biol. 2019. PMID: 31265828 No abstract available.

2

The Pneumococcal Divisome: Dynamic Control of Streptococcus pneumoniae Cell Division.

Briggs NS, Bruce KE, Naskar S, Winkler ME, Roper DI. Briggs NS, et al. Front Microbiol. 2021 Oct 18;12:737396. doi: 10.3389/fmicb.2021.737396. eCollection 2021. Front Microbiol. 2021. PMID: 34737730 Free PMC article. Review.

3

Bacterial cell wall assembly: still an attractive antibacterial target.

Bugg TD, Braddick D, Dowson CG, Roper DI. Bugg TD, et al. Trends Biotechnol. 2011 Apr;29(4):167-73. doi: 10.1016/j.tibtech.2010.12.006. Epub 2011 Jan 12. Trends Biotechnol. 2011. PMID: 21232809 Review.

4

Detection of "Hidden" Antimicrobial Drug Resistance.

Hu Q, Yu Y, Gu D, Xie L, Chen X, Xu N, Ruan JJ, Dowson C, Ruan BH. Hu Q, et al. ACS Infect Dis. 2019 Jul 12;5(7):1252-1263. doi: 10.1021/acsinfecdis.9b00132. Epub 2019 Jun 20. ACS Infect Dis. 2019. PMID: 31243989

5

Core Steps of Membrane-Bound Peptidoglycan Biosynthesis: Recent Advances, Insight and Opportunities.

Teo AC, Roper DI. Teo AC, et al. Antibiotics (Basel). 2015 Nov 3;4(4):495-520. doi: 10.3390/antibiotics4040495. Antibiotics (Basel). 2015. PMID: 27025638 Free PMC article. Review.

6

Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of β-Lactam Target-Mediated Resistance.

Bellini D, Koekemoer L, Newman H, Dowson CG. Bellini D, et al. J Mol Biol. 2019 Aug 23;431(18):3501-3519. doi: 10.1016/j.jmb.2019.07.010. Epub 2019 Jul 10. J Mol Biol. 2019. PMID: 31301409

7

Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane.

York A, Lloyd AJ, Del Genio CI, Shearer J, Hinxman KJ, Fritz K, Fulop V, Dowson CG, Khalid S, Roper DI. York A, et al. Structure. 2021 Jul 1;29(7):731-742.e6. doi: 10.1016/j.str.2021.03.001. Epub 2021 Mar 18. Structure. 2021. PMID: 33740396 Free PMC article.

8

A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.

Micelli C, Dai Y, Raustad N, Isberg RR, Dowson CG, Lloyd AJ, Geisinger E, Crow A, Roper DI. Micelli C, et al. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215237120. doi: 10.1073/pnas.2215237120. Epub 2023 Feb 14. Proc Natl Acad Sci U S A. 2023. PMID: 36787358 Free PMC article.

9

A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae.

Aggarwal SD, Lloyd AJ, Yerneni SS, Narciso AR, Shepherd J, Roper DI, Dowson CG, Filipe SR, Hiller NL. Aggarwal SD, et al. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2018089118. doi: 10.1073/pnas.2018089118. Proc Natl Acad Sci U S A. 2021. PMID: 33785594 Free PMC article.

10

Adenosine tetraphosphoadenosine drives a continuous ATP-release assay for aminoacyl-tRNA synthetases and other adenylate-forming enzymes.

Lloyd AJ, Potter NJ, Fishwick CW, Roper DI, Dowson CG. Lloyd AJ, et al. ACS Chem Biol. 2013 Oct 18;8(10):2157-63. doi: 10.1021/cb400248f. Epub 2013 Aug 13. ACS Chem Biol. 2013. PMID: 23898887 Free article.

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