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CD163, a marker of perivascular macrophages, is up-regulated by microglia in simian immunodeficiency virus encephalitis after haptoglobin-hemoglobin complex stimulation and is suggestive of breakdown of the blood-brain barrier.
Borda JT, Alvarez X, Mohan M, Hasegawa A, Bernardino A, Jean S, Aye P, Lackner AA. Borda JT, et al. Am J Pathol. 2008 Mar;172(3):725-37. doi: 10.2353/ajpath.2008.070848. Epub 2008 Feb 14. Am J Pathol. 2008. PMID: 18276779 Free PMC article.