G2022003F/BrightFocus Foundation[Grants and Funding] - Search Results

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A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells.

Harkin J, Peña KH, Gomes C, Hernandez M, Lavekar SS, So K, Lentsch K, Feder EM, Morrow S, Huang KC, Tutrow KD, Morris A, Zhang C, Meyer JS. Harkin J, et al. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2317285121. doi: 10.1073/pnas.2317285121. Epub 2024 Jun 13. Proc Natl Acad Sci U S A. 2024. PMID: 38870053 Free PMC article.

Exploring dysfunctional barrier phenotypes associated with glaucoma using a human pluripotent stem cell-based model of the neurovascular unit.

Lavekar SS, Hughes JM, Gomes C, Huang KC, Harkin J, Canfield SG, Meyer JS. Lavekar SS, et al. Fluids Barriers CNS. 2024 Nov 14;21(1):90. doi: 10.1186/s12987-024-00593-x. Fluids Barriers CNS. 2024. PMID: 39543684 Free PMC article.

Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction.

Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Hetzer SM, Patil SV, Di Polo A, Meyer JS. Huang KC, et al. Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2. Acta Neuropathol Commun. 2024. PMID: 39425218 Free PMC article.

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