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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1884 1
1885 1
1886 1
1887 2
1890 1
1895 10
1896 2
1900 1
1903 1
1904 1
1910 3
1911 1
1914 1
1917 1
1920 1
1947 1
1950 1
1954 1
1956 1
1957 2
1958 1
1959 2
1960 1
1961 4
1962 5
1963 1
1964 4
1965 2
1966 3
1967 3
1968 4
1969 2
1970 6
1971 6
1972 4
1973 3
1975 6
1976 7
1977 5
1978 4
1979 10
1980 6
1981 13
1982 11
1983 3
1984 5
1985 5
1986 6
1987 18
1988 11
1989 5
1990 10
1991 13
1992 11
1993 5
1994 13
1995 17
1996 9
1997 16
1998 13
1999 10
2000 12
2001 16
2002 16
2003 13
2004 5
2005 13
2006 7
2007 10
2008 10
2009 16
2010 21
2011 15
2012 17
2013 14
2014 10
2015 12
2016 12
2017 13
2018 14
2019 19
2020 24
2021 26
2022 20
2023 21
2024 20
2025 1

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669 results

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Page 1
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.
Schulze CJ, Seamon KJ, Zhao Y, Yang YC, Cregg J, Kim D, Tomlinson A, Choy TJ, Wang Z, Sang B, Pourfarjam Y, Lucas J, Cuevas-Navarro A, Ayala-Santos C, Vides A, Li C, Marquez A, Zhong M, Vemulapalli V, Weller C, Gould A, Whalen DM, Salvador A, Milin A, Saldajeno-Concar M, Dinglasan N, Chen A, Evans J, Knox JE, Koltun ES, Singh M, Nichols R, Wildes D, Gill AL, Smith JAM, Lito P. Schulze CJ, et al. Among authors: gould a. Science. 2023 Aug 18;381(6659):794-799. doi: 10.1126/science.adg9652. Epub 2023 Aug 17. Science. 2023. PMID: 37590355 Free PMC article.
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
Zani F, Blagih J, Gruber T, Buck MD, Jones N, Hennequart M, Newell CL, Pilley SE, Soro-Barrio P, Kelly G, Legrave NM, Cheung EC, Gilmore IS, Gould AP, Garcia-Caceres C, Vousden KH. Zani F, et al. Among authors: gould ap. Nature. 2023 Mar;615(7953):705-711. doi: 10.1038/s41586-023-05801-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922598 Free PMC article.
Repeated blood-brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial.
Sonabend AM, Gould A, Amidei C, Ward R, Schmidt KA, Zhang DY, Gomez C, Bebawy JF, Liu BP, Bouchoux G, Desseaux C, Helenowski IB, Lukas RV, Dixit K, Kumthekar P, Arrieta VA, Lesniak MS, Carpentier A, Zhang H, Muzzio M, Canney M, Stupp R. Sonabend AM, et al. Among authors: gould a. Lancet Oncol. 2023 May;24(5):509-522. doi: 10.1016/S1470-2045(23)00112-2. Lancet Oncol. 2023. PMID: 37142373 Free PMC article. Clinical Trial.
The proteasome as a target for protozoan parasites.
Xie SC, Dick LR, Gould A, Brand S, Tilley L. Xie SC, et al. Among authors: gould a. Expert Opin Ther Targets. 2019 Nov;23(11):903-914. doi: 10.1080/14728222.2019.1685981. Epub 2019 Nov 4. Expert Opin Ther Targets. 2019. PMID: 31679410 Free article. Review.
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Xie SC, Metcalfe RD, Dunn E, Morton CJ, Huang SC, Puhalovich T, Du Y, Wittlin S, Nie S, Luth MR, Ma L, Kim MS, Pasaje CFA, Kumpornsin K, Giannangelo C, Houghton FJ, Churchyard A, Famodimu MT, Barry DC, Gillett DL, Dey S, Kosasih CC, Newman W, Niles JC, Lee MCS, Baum J, Ottilie S, Winzeler EA, Creek DJ, Williamson N, Parker MW, Brand S, Langston SP, Dick LR, Griffin MDW, Gould AE, Tilley L. Xie SC, et al. Among authors: gould ae. Science. 2022 Jun 3;376(6597):1074-1079. doi: 10.1126/science.abn0611. Epub 2022 Jun 2. Science. 2022. PMID: 35653481 Free PMC article.
Metabolic decisions in development and disease-a Keystone Symposia report.
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. Cable J, et al. Among authors: gould ap. Ann N Y Acad Sci. 2021 Dec;1506(1):55-73. doi: 10.1111/nyas.14678. Epub 2021 Aug 19. Ann N Y Acad Sci. 2021. PMID: 34414571 Review.
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.
Kim KS, Habashy K, Gould A, Zhao J, Najem H, Amidei C, Saganty R, Arrieta VA, Dmello C, Chen L, Zhang DY, Castro B, Billingham L, Levey D, Huber O, Marques M, Savitsky DA, Morin BM, Muzzio M, Canney M, Horbinski C, Zhang P, Miska J, Padney S, Zhang B, Rabadan R, Phillips JJ, Butowski N, Heimberger AB, Hu J, Stupp R, Chand D, Lee-Chang C, Sonabend AM. Kim KS, et al. Among authors: gould a. Neuro Oncol. 2024 Nov 4;26(11):2044-2060. doi: 10.1093/neuonc/noae135. Neuro Oncol. 2024. PMID: 39028616
Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma.
Wu Y, Chen S, Yang X, Sato K, Lal P, Wang Y, Shinkle AT, Wendl MC, Primeau TM, Zhao Y, Gould A, Sun H, Mudd JL, Hoog J, Mashl RJ, Wyczalkowski MA, Mo CK, Liu R, Herndon JM, Davies SR, Liu D, Ding X, Evrard YA, Welm BE, Lum D, Koh MY, Welm AL, Chuang JH, Moscow JA, Meric-Bernstam F, Govindan R, Li S, Hsieh J, Fields RC, Lim KH, Ma CX, Zhang H, Ding L, Chen F. Wu Y, et al. Among authors: gould a. Cancer Res. 2023 Dec 15;83(24):4161-4178. doi: 10.1158/0008-5472.CAN-23-0604. Cancer Res. 2023. PMID: 38098449 Free PMC article.
A framework for assessing the impact of accelerated approval.
Gould AL, Campbell RK, Loewy JW, Beckman RA, Dey J, Schiel A, Burman CF, Zhou J, Antonijevic Z, Miller ER, Tang R. Gould AL, et al. PLoS One. 2022 Jun 24;17(6):e0265712. doi: 10.1371/journal.pone.0265712. eCollection 2022. PLoS One. 2022. PMID: 35749431 Free PMC article.
669 results